iGMDRD929

Loading, please wait...
Standard Name
DRUGBANK ID
Drug Status
Drug Type
Standard NameIpilimumab
DRUGBANK IDDB06186
Drug StatusAlone
Drug TypeBiotech

Drug Targets:

CTLA4 (P16410)

Drug-model tissue-cancer distribution: Bubble Plot

LYMPtissue: LYMP cancer: LYMPH model num: 0LYMPHtissue: LYMPH cancer: Sezary Syndrome (SEZS) model num: 1SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: Melanoma (MEL) model num: 1

Drug-gene pathway enrichments

1reactome: PD-1 signaling1reactome: Costimulation by the CD28 family1reactome: Immune System1reactome: Adaptive Immune System1kegg: Cell adhesion molecules (CAMs) - Homo sapiens (human)

Drug-gene GO enrichments

3BP: T cell costimulation2BP: cell surface receptor signaling pathway2BP: immune response2BP: signal transduction2BP: positive regulation of T cell proliferation2CC: plasma membrane2CC: external side of plasma membrane1BP: cellular response to lipopolysaccharide1BP: negative regulation of activated T cell proliferation1BP: regulation of activated T cell proliferation

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
29126 CD274 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Models in Ipilimumab

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.