iGMDRD933

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Standard Name
Drug Status
Drug Type
Standard NameJAK inhibitor (alone or in combination)
Drug StatusFamily/Alone/Combination
Drug Typeundefined

Drug-model tissue-cancer distribution: Bubble Plot

BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: Acute Myeloid Leukemia (AML) model num: 2

Drug-gene pathway enrichments

2reactome: Interleukin-12 family signaling2reactome: Interferon gamma signaling2reactome: Interleukin-6 signaling2reactome: Signaling by Interleukins2reactome: Interleukin-3, Interleukin-5 and GM-CSF signaling2reactome: Interleukin-6 family signaling2reactome: Interferon Signaling2reactome: Immune System2reactome: Regulation of IFNG signaling2reactome: Interleukin-12 signaling

Drug-gene GO enrichments

4BP: cytokine-mediated signaling pathway4MF: protein tyrosine kinase activity2MF: histone kinase activity (H3-Y41 specific)2MF: growth hormone receptor binding2BP: histone H3-Y41 phosphorylation2BP: JAK-STAT cascade involved in growth hormone signaling pathway2BP: interleukin-12-mediated signaling pathway2BP: erythrocyte differentiation2BP: tyrosine phosphorylation of STAT protein2CC: nucleoplasm

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3717 JAK2 2
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Gene in drug-gene network: Network Plot

Models in JAK inhibitor (alone or in combination)

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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