iGMDRD964

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Standard Name
DRUGBANK ID
Drug Status
Drug Type
Standard NameOMP-59R5
DRUGBANK IDDB12104
Drug StatusAlone
Drug TypeBiotech

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: SOLID Cancers model num: 2

Drug-gene pathway enrichments

3wikipathways: Notch Signaling Pathway2reactome: Pre-NOTCH Processing in Golgi2reactome: Pre-NOTCH Transcription and Translation2reactome: Generic Transcription Pathway2reactome: Pre-NOTCH Expression and Processing2reactome: Signaling by NOTCH12reactome: NOTCH1 Intracellular Domain Regulates Transcription2reactome: Activated NOTCH1 Transmits Signal to the Nucleus2reactome: Signaling by NOTCH2reactome: RNA Polymerase II Transcription

Drug-gene GO enrichments

3BP: aortic valve morphogenesis3BP: Notch signaling pathway2BP: pulmonary valve morphogenesis2CC: plasma membrane2BP: positive regulation of transcription by RNA polymerase II2BP: positive regulation of transcription of Notch receptor target2CC: nucleus2BP: positive regulation of cell proliferation1BP: cardiac septum morphogenesis1BP: arterial endothelial cell differentiation

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
4851 NOTCH1 2
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Gene in drug-gene network: Network Plot

Models in OMP-59R5

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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