iGMDRD972

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Standard Name
DRUGBANK ID
Drug Status
Drug Type
Standard NamePatritumab
DRUGBANK IDDB12090
Drug StatusAlone
Drug TypeBiotech

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: Non-Small Cell Lung Cancer (NSCLC) model num: 1

Drug-gene pathway enrichments

2reactome: SHC1 events in ERBB2 signaling2reactome: Signaling by Receptor Tyrosine Kinases2reactome: Signaling by ERBB42reactome: Signal Transduction2reactome: Signaling by ERBB21wikipathways: MicroRNAs in cardiomyocyte hypertrophy1wikipathways: Cardiac Progenitor Differentiation1wikipathways: Cardiac Hypertrophic Response1pharmgkb: EGFR Inhibitor Pathway, Pharmacodynamics1reactome: Signaling by Non-Receptor Tyrosine Kinases

Drug-gene GO enrichments

2BP: nervous system development2BP: activation of transmembrane receptor protein tyrosine kinase activity2CC: extracellular region2BP: ERBB signaling pathway1BP: positive regulation of striated muscle cell differentiation1BP: negative regulation of secretion1BP: positive regulation of peptidyl-tyrosine phosphorylation1BP: positive regulation of protein kinase B signaling1BP: cardiac muscle cell differentiation1BP: oligodendrocyte differentiation

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3084 NRG1 1
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Gene in drug-gene network: Network Plot

Models in Patritumab

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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