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PDGFR inhibitor
iGMDRD976
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Standard Name
Drug Status
Drug Type
Standard Name
PDGFR inhibitor
Drug Status
Family
Drug Type
undefined
Drug Class:
Kinase Inhibitor
Protein Kinase Inhibitors
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Drug-model tissue-cancer distribution: Bubble Plot
BRAI
tissue: BRAI cancer: BRAIN model num: 0
BRAIN
tissue: BRAIN cancer: Glioma model num: 2
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Drug-gene pathway enrichments
1
kegg: Choline metabolism in cancer - Homo sapiens (human)
1
kegg: Central carbon metabolism in cancer - Homo sapiens (human)
1
biocarta: role of pi3k subunit p85 in regulation of actin organization and cell migration
1
biocarta: phospholipids as signalling intermediaries
1
biocarta: rac1 cell motility signaling pathway
1
biocarta: pdgf signaling pathway
1
kegg: Melanoma - Homo sapiens (human)
1
kegg: Prostate cancer - Homo sapiens (human)
1
kegg: HTLV-I infection - Homo sapiens (human)
1
kegg: Regulation of actin cytoskeleton - Homo sapiens (human)
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Drug-gene GO enrichments
3
MF: platelet-derived growth factor alpha-receptor activity
3
MF: platelet-derived growth factor binding
2
CC: integral component of plasma membrane
2
MF: transmembrane receptor protein tyrosine kinase activity
2
CC: plasma membrane
2
CC: nucleus
2
BP: embryonic cranial skeleton morphogenesis
2
BP: positive regulation of ERK1 and ERK2 cascade
2
CC: cytoplasm
2
BP: positive regulation of cell migration
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Drug-Gene: Aster Plot
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Gene ID
Gene Name
Model Num.
5156
PDGFRA
2
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4
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1
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Gene in drug-gene network: Network Plot
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Models in PDGFR inhibitor
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found
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