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RET inhibitor
iGMDRD999
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Standard Name
Drug Status
Drug Type
Standard Name
RET inhibitor
Drug Status
Family
Drug Type
Small Molecule
Drug Class:
Kinase Inhibitor
Protein Kinase Inhibitors
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Drug-model tissue-cancer distribution: Bubble Plot
LUN
tissue: LUN cancer: LUNG model num: 0
LUNG
tissue: LUNG cancer: Lung Adenocarcinoma (LUAD) model num: 2
LUNG
tissue: LUNG cancer: Adenoid Cystic Carcinoma of the Lung (LUACC) model num: 2
THYROI
tissue: THYROI cancer: THYROID model num: 0
THYROID
tissue: THYROID cancer: Thyroid Cancer model num: 6
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Drug-gene pathway enrichments
1
pharmgkb: Pathway_PA165959425
1
kegg: Central carbon metabolism in cancer - Homo sapiens (human)
1
kegg: Thyroid cancer - Homo sapiens (human)
1
pharmgkb: Sorafenib Pharmacodynamics
1
wikipathways: Aryl Hydrocarbon Receptor
1
wikipathways: Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways
1
wikipathways: Dopaminergic Neurogenesis
1
kegg: Pathways in cancer - Homo sapiens (human)
1
pid: Signaling events regulated by Ret tyrosine kinase
1
reactome: RAF/MAP kinase cascade
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Drug-gene GO enrichments
3
MF: transmembrane receptor protein tyrosine kinase activity
2
CC: receptor complex
2
CC: plasma membrane
2
CC: axon
2
CC: integral component of plasma membrane
2
MF: protein tyrosine kinase activity
1
CC: early endosome
1
BP: Peyer's patch morphogenesis
1
CC: cytosol
1
BP: innervation
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Drug-Gene: Aster Plot
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Gene ID
Gene Name
Model Num.
5979
RET
4
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4
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1
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Gene in drug-gene network: Network Plot
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Models in RET inhibitor
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found
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