UST
Summary: Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:610752 Ensembl IDEnsembl:ENSG00000111962 HGNC IDHGNC:HGNC:17223 PHARMGKB IDPA38213 Map Location6q25.1 | |||||
GO terms in UST
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0000139 | Golgi membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| BP | TAS | GO:0006477 | protein sulfation |
| BP | IEA | GO:0030010 | establishment of cell polarity |
| BP | TAS | GO:0030208 | dermatan sulfate biosynthetic process |
| BP | IEA | GO:0050770 | regulation of axonogenesis |
Gene expression in normal tissue: UST
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in UST
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| humancyc | PWY-6567 | chondroitin sulfate biosynthesis (late stages) |
| humancyc | PWY-6568 | dermatan sulfate biosynthesis (late stages) |
| humancyc | PWY-6569 | chondroitin sulfate biosynthesis |
| humancyc | PWY-6571 | dermatan sulfate biosynthesis |
| kegg | hsa00532 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate - Homo sapiens (human) |
| reactome | R-HSA-1430728 | Metabolism |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD491 | TAE-684 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in UST
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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