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Summary: Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
uronyl 2-sulfotransferase	MIM:610752	Ensembl:ENSG00000111962	HGNC:HGNC:17223	PA38213	6q25.1

GO terms in UST

Term Type	Evidence Type	GO Term ID	GO Des.
CC	TAS	GO:0000139	Golgi membrane
CC	IEA	GO:0016021	integral component of membrane
BP	TAS	GO:0006477	protein sulfation
BP	IEA	GO:0030010	establishment of cell polarity
BP	TAS	GO:0030208	dermatan sulfate biosynthetic process
BP	IEA	GO:0050770	regulation of axonogenesis
MF	IBA	GO:0008146	sulfotransferase activity
MF	TAS	GO:0008146	sulfotransferase activity

Gene expression in normal tissue: UST

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in UST

Database	Pathway ID	Pathway Des.
humancyc	PWY-6567	chondroitin sulfate biosynthesis (late stages)
humancyc	PWY-6568	dermatan sulfate biosynthesis (late stages)
humancyc	PWY-6569	chondroitin sulfate biosynthesis
humancyc	PWY-6571	dermatan sulfate biosynthesis
kegg	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate - Homo sapiens (human)
reactome	R-HSA-1430728	Metabolism
reactome	R-HSA-1630316	Glycosaminoglycan metabolism
reactome	R-HSA-1793185	Chondroitin sulfate/dermatan sulfate metabolism
reactome	R-HSA-2022923	Dermatan sulfate biosynthesis
reactome	R-HSA-71387	Metabolism of carbohydrates

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD491	TAE-684	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in UST

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