PPP1R13L


Summary: IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in PPP1R13L


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Term Type
Evidence Type
GO Term ID
GO Des.
CC TAS GO:0005634 nucleus
CC TAS GO:0005654 nucleoplasm
CC IDA GO:0005829 cytosol
CC IDA GO:0030054 cell junction
CC IDA GO:0045171 intercellular bridge
BP IEA GO:0000122 negative regulation of transcription by RNA polymerase II
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Gene expression in normal tissue: PPP1R13L

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Breast cancer1

Pathways in PPP1R13L


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Database
Pathway ID
Pathway Des.
reactome R-HSA-212436 Generic Transcription Pathway
reactome R-HSA-3700989 Transcriptional Regulation by TP53
reactome R-HSA-5633007 Regulation of TP53 Activity
reactome R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors
reactome R-HSA-73857 RNA Polymerase II Transcription
reactome R-HSA-74160 Gene expression (Transcription)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD133 Lapatinib 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PPP1R13L

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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