CHGB
Summary: This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| chromogranin B | MIM:118920 | Ensembl:ENSG00000089199 | HGNC:HGNC:1930 | PA26462 | 20p12.3 |
GO terms in CHGB
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0005576 | extracellular region |
| CC | IBA | GO:0005615 | extracellular space |
| CC | TAS | GO:0005788 | endoplasmic reticulum lumen |
| CC | IBA | GO:0030141 | secretory granule |
| CC | IEA | GO:0030141 | secretory granule |
| BP | IEA | GO:0010469 | regulation of signaling receptor activity |
| BP | TAS | GO:0043687 | post-translational protein modification |
| BP | TAS | GO:0044267 | cellular protein metabolic process |
| MF | TAS | GO:0005179 | hormone activity |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: CHGB
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CHGB
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-381426 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-597592 | Post-translational protein modification |
| reactome | R-HSA-8957275 | Post-translational protein phosphorylation |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CHGB
CLASSFICATION
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