FOXP4


Summary: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
forkhead box P4MIM:608924Ensembl:ENSG00000137166HGNC:HGNC:20842PA1349430986p21.1

GO terms in FOXP4


Term TypeEvidence TypeGO Term IDGO Des.
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISMGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIPIGO:0005515protein binding
MFIEAGO:0043565sequence-specific DNA binding
MFIEAGO:0046872metal ion binding
BPIEAGO:0006351transcription, DNA-templated
BPIEAGO:0006357regulation of transcription by RNA polymerase II

Gene expression in normal tissue: FOXP4

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in FOXP4


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011
iGMDRD131Erlotinib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FOXP4

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