PIP5KL1
Summary: PIP5KL1 is a phosphoinositide kinase-like protein that lacks intrinsic lipid kinase activity but associates with type I PIPKs (see PIP5K1A; MIM 603275) and may play a role in localization of PIPK activity (Chang et al., 2004 [PubMed 14701839]).[supplied by OMIM, Jun 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:612865 Ensembl IDEnsembl:ENSG00000167103 HGNC IDHGNC:HGNC:28711 PHARMGKB IDPA134926015 Map Location9q34.11 | |||||
Gene Categories:
KINASEGO terms in PIP5KL1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0005524 | ATP binding |
| MF | IEA | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity |
| CC | IDA | GO:0005829 | cytosol |
| CC | IEA | GO:0016020 | membrane |
| CC | IEA | GO:0042995 | cell projection |
| BP | IEA | GO:0046854 | phosphatidylinositol phosphorylation |
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Gene expression in normal tissue: PIP5KL1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PIP5KL1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP51 | Regulation of Actin Cytoskeleton |
| kegg | hsa00562 | Inositol phosphate metabolism - Homo sapiens (human) |
| kegg | hsa04144 | Endocytosis - Homo sapiens (human) |
| humancyc | PWY-6351 | D-myo-inositol (1,4,5)-trisphosphate biosynthesis |
| humancyc | PWY-6352 | 3-phosphoinositide biosynthesis |
| humancyc | PWY-6371 | superpathway of inositol phosphate compounds |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PIP5KL1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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