PIP5KL1


Summary: PIP5KL1 is a phosphoinositide kinase-like protein that lacks intrinsic lipid kinase activity but associates with type I PIPKs (see PIP5K1A; MIM 603275) and may play a role in localization of PIPK activity (Chang et al., 2004 [PubMed 14701839]).[supplied by OMIM, Jun 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
phosphatidylinositol-4-phosphate 5-kinase like 1MIM:612865Ensembl:ENSG00000167103HGNC:HGNC:28711PA1349260159q34.11

Gene Categories:

KINASE

GO terms in PIP5KL1


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0005524ATP binding
MFIEAGO:00163081-phosphatidylinositol-4-phosphate 5-kinase activity
CCIDAGO:0005829cytosol
CCIEAGO:0016020membrane
CCIEAGO:0042995cell projection
BPIEAGO:0046854phosphatidylinositol phosphorylation

Gene expression in normal tissue: PIP5KL1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PIP5KL1


DatabasePathway IDPathway Des.
wikipathwaysWP51Regulation of Actin Cytoskeleton
kegghsa00562Inositol phosphate metabolism - Homo sapiens (human)
kegghsa04144Endocytosis - Homo sapiens (human)
humancycPWY-6351D-myo-inositol (1,4,5)-trisphosphate biosynthesis
humancycPWY-63523-phosphoinositide biosynthesis
humancycPWY-6371superpathway of inositol phosphate compounds

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD255SB2250023
iGMDRD61Kinetin riboside6

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PIP5KL1

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