BNIPL
Summary: The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| BCL2 interacting protein like | MIM:611275 | Ensembl:ENSG00000163141 | HGNC:HGNC:16976 | PA38196 | 1q21.3 |
GO terms in BNIPL
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0006798 | polyphosphate catabolic process |
| BP | IBA | GO:0006915 | apoptotic process |
| BP | IDA | GO:0006915 | apoptotic process |
| BP | IDA | GO:0008285 | negative regulation of cell proliferation |
| BP | IDA | GO:0040009 | regulation of growth rate |
| CC | IDA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005829 | cytosol |
| MF | IBA | GO:0004309 | exopolyphosphatase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IPI | GO:0042802 | identical protein binding |
Gene expression in normal tissue: BNIPL
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in BNIPL
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in BNIPL
CLASSFICATION
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