APLF

Summary: C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM, Mar 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameaprataxin and PNKP like factor
OMIM IDMIM:611035
Ensembl IDEnsembl:ENSG00000169621
HGNC IDHGNC:HGNC:28724
PHARMGKB IDPA164715842
Map Location2p13.3

Gene Categories:

DNA REPAIR

GO terms in APLF


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IDA GO:0000166 nucleotide binding
MF IBA GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
MF IDA GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
MF IDA GO:0004520 endodeoxyribonuclease activity
MF IPI GO:0005515 protein binding
MF IDA GO:0008408 3'-5' exonuclease activity
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Gene expression in normal tissue: APLF

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in APLF


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Database
Pathway ID
Pathway Des.
pid dnapk_pathway DNA-PK pathway in nonhomologous end joining
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD536 PLX-4720 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in APLF

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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