iGMDRD536
| Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
| PLX-4720 | CHEMBL1230020 | 24180700 | DB06999 | Alone | Small Molecule |
Drug Targets:
BRAF (P15056)Drug Pathways:
ERK MAPK signalingDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 100287296 | LINC00265-2P | 2 |
| 10636 | RGS14 | 1 |
| 55827 | DCAF6 | 2 |
| 348926 | FAM86EP | 1 |
| 84553 | FAXC | 1 |
| 2956 | MSH6 | 1 |
| 3845 | KRAS | 1 |
| 5295 | PIK3R1 | 1 |
| 599 | BCL2L2 | 1 |
| 57545 | CC2D2A | 1 |
| 692215 | SNORD112 | 1 |
| 2161 | F12 | 1 |
| 6597 | SMARCA4 | 1 |
| 1393 | CRHBP | 1 |
| 79820 | CATSPERB | 1 |
| 57580 | PREX1 | 1 |
| 4771 | NF2 | 1 |
| 128553 | TSHZ2 | 1 |
| 6598 | SMARCB1 | 1 |
| 28999 | KLF15 | 1 |
| 6258 | RXRG | 1 |
| 29114 | TAGLN3 | 2 |
| 1500 | CTNND1 | 1 |
| 11329 | STK38 | 1 |
| 497258 | BDNF-AS | 1 |
| 5596 | MAPK4 | 1 |
| 25941 | TPGS2 | 1 |
| 2625 | GATA3 | 1 |
| 221960 | CCZ1B | 1 |
| 8242 | KDM5C | 1 |
| 4851 | NOTCH1 | 1 |
| 7158 | TP53BP1 | 1 |
| 55294 | FBXW7 | 1 |
| 200558 | APLF | 1 |
| 1021 | CDK6 | 1 |
| 4108 | MAGEA9 | 1 |
| 4610 | MYCL | 1 |
| 25937 | WWTR1 | 1 |
| 91227 | GGTLC2 | 1 |
| 619279 | ZNF704 | 1 |
| 4300 | MLLT3 | 1 |
| 7416 | VDAC1 | 1 |
| 3363 | HTR7 | 1 |
| 51343 | FZR1 | 1 |
| 55277 | FGGY | 1 |
| 7348 | UPK1B | 1 |
| 100129480 | MKRN2OS | 1 |
| 160140 | C11orf65 | 1 |
| 101927152 | SAMMSON | 1 |
| 7428 | VHL | 1 |
| 2064 | ERBB2 | 3 |
| 5621 | PRNP | 1 |
| 83707 | TRPT1 | 1 |
| 6416 | MAP2K4 | 1 |
| 10232 | MSLN | 1 |
| 255928 | SYT14 | 1 |
| 200895 | DHFR2 | 1 |
| 2778 | GNAS | 1 |
| 80243 | PREX2 | 1 |
| 472 | ATM | 1 |
| 139285 | AMER1 | 1 |
| 57158 | JPH2 | 1 |
| 84263 | HSDL2 | 1 |
| 22933 | SIRT2 | 1 |
| 1182 | CLCN3 | 1 |
| 1029 | CDKN2A | 1 |
| 861 | RUNX1 | 1 |
| 100302146 | MIR1302-5 | 1 |
| 3781 | KCNN2 | 1 |
| 10018 | BCL2L11 | 1 |
| 7157 | TP53 | 1 |
| 6794 | STK11 | 1 |
| 677681 | SCARNA20 | 2 |
| 4292 | MLH1 | 1 |
| 54498 | SMOX | 1 |
| 311 | ANXA11 | 2 |
| 1019 | CDK4 | 2 |
| 25874 | MPC2 | 2 |
| 54543 | TOMM7 | 1 |
| 219749 | ZNF25 | 1 |
| 2309 | FOXO3 | 1 |
| 285600 | KIAA0825 | 2 |
| 100286918 | NDUFS5P2 | 1 |
| 3157 | HMGCS1 | 1 |
| 57111 | RAB25 | 1 |
| 4089 | SMAD4 | 1 |
| 50944 | SHANK1 | 1 |
| 148756 | OVAAL | 1 |
| 106479214 | RN7SKP266 | 1 |
| 3417 | IDH1 | 1 |
| 8731 | RNMT | 1 |
| 5290 | PIK3CA | 1 |
| 116535 | MRGPRF | 1 |
| 64919 | BCL11B | 1 |
| 101928846 | HIPK1-AS1 | 1 |
| 675 | BRCA2 | 1 |
| 255738 | PCSK9 | 1 |
| 100507420 | LINC01605 | 1 |
| 1956 | EGFR | 1 |
| 100873624 | RNA5SP365 | 1 |
| 8792 | TNFRSF11A | 1 |
| 4609 | MYC | 1 |
| 4973 | OLR1 | 2 |
| 1031 | CDKN2C | 1 |
| 106479749 | RNU6-414P | 1 |
| 5156 | PDGFRA | 1 |
| 81796 | SLCO5A1 | 1 |
| 673 | BRAF | 18 |
| 729522 | AACSP1 | 1 |
| 55249 | YY1AP1 | 2 |
| 147920 | IGFL2 | 1 |
| 285175 | UNC80 | 1 |
| 55771 | PRR11 | 1 |
| 10253 | SPRY2 | 2 |
| 22903 | BTBD3 | 1 |
| 100422909 | MIR4295 | 1 |
| 5728 | PTEN | 1 |
| 208 | AKT2 | 1 |
| 2026 | ENO2 | 2 |
| 64222 | TOR3A | 2 |
| 4521 | NUDT1 | 1 |
| 9214 | FCMR | 1 |
| 2825 | GPR1 | 1 |
| 343702 | XKR7 | 1 |
| 7059 | THBS3 | 1 |
| 100128448 | UQCRHP4 | 2 |
| 201617 | LINC00870 | 1 |
| 440 | ASNS | 1 |
| 158326 | FREM1 | 1 |
| 65983 | GRAMD2B | 1 |
| 100873405 | RNA5SP137 | 2 |
| 27314 | RAB30 | 1 |
| 5909 | RAP1GAP | 1 |
| 1288 | COL4A6 | 1 |
| 2776 | GNAQ | 1 |
| 5695 | PSMB7 | 1 |
| 1719 | DHFR | 1 |
| 6196 | RPS6KA2 | 1 |
| 100873861 | RNU1-19P | 1 |
| 51693 | TRAPPC2L | 1 |
| 3717 | JAK2 | 1 |
| 134728 | IRAK1BP1 | 1 |
| 83592 | AKR1E2 | 1 |
| 50861 | STMN3 | 1 |
| 4090 | SMAD5 | 1 |
| 3977 | LIFR | 1 |
| 201163 | FLCN | 1 |
| 285382 | C3orf70 | 1 |
| 2122 | MECOM | 1 |
| 10168 | ZNF197 | 1 |
| 728269 | MAGEA9B | 2 |
| 100873064 | AIMP1P2 | 1 |
| 5925 | RB1 | 1 |
| 4893 | NRAS | 5 |
| 100271386 | RPS4XP20 | 2 |
| 55251 | PCMTD2 | 1 |
| 9146 | HGS | 1 |
| 106481950 | RNU6-1315P | 2 |
| 7403 | KDM6A | 1 |
| 9229 | DLGAP1 | 1 |
| 2649 | NR6A1 | 1 |
| 2261 | FGFR3 | 1 |
| 581 | BAX | 1 |
| 3483 | IGFALS | 1 |
| 595 | CCND1 | 1 |
| 4763 | NF1 | 1 |
| 4613 | MYCN | 1 |
| 9644 | SH3PXD2A | 1 |
| 5540 | NPY4R | 1 |
| 677768 | SCARNA13 | 1 |
| 100533676 | PHACTR2P1 | 1 |
| 29118 | DDX25 | 1 |
| 3265 | HRAS | 1 |
| 4193 | MDM2 | 1 |
| 1499 | CTNNB1 | 1 |
| 2146 | EZH2 | 1 |
| 441893 | GAPDHP29 | 1 |
| 5624 | PROC | 2 |
| 644524 | NKX2-4 | 1 |
| 3169 | FOXA1 | 1 |
Gene in drug-gene network: Network Plot
Models in PLX-4720
CLASSFICATION
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