CTNND1
Summary: This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Namecatenin delta 1 OMIM IDMIM:601045 Ensembl IDEnsembl:ENSG00000198561 HGNC IDHGNC:HGNC:2515 PHARMGKB IDPA27016 Map Location11q12.1 | |||||
GO terms in CTNND1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005102 | signaling receptor binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0019901 | protein kinase binding |
| MF | HDA | GO:0045296 | cadherin binding |
| MF | IBA | GO:0045296 | cadherin binding |
| MF | IPI | GO:0045296 | cadherin binding |
Gene expression in normal tissue: CTNND1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CTNND1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP3888 | VEGFA-VEGFR2 Signaling Pathway |
| wikipathways | WP399 | Wnt Signaling Pathway and Pluripotency |
| kegg | hsa04015 | Rap1 signaling pathway - Homo sapiens (human) |
| kegg | hsa04520 | Adherens junction - Homo sapiens (human) |
| kegg | hsa04670 | Leukocyte transendothelial migration - Homo sapiens (human) |
| pid | ajdiss_2pathway | Posttranslational regulation of adherens junction stability and dissassembly |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CTNND1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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