iGMDRD409


Canonical SMILES: CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

InChI: InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)

InChI Key: OUKYUETWWIPKQR-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
SaracatinibCHEMBL217092 10302500DB11805AloneSmall Molecule


Drug Targets:

SRCABL1EGFR

Drug Pathways:

RTK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
100271218RPL7P361
223ALDH9A11
400954EML62
7514XPO11
84264HAGHL1
259173ALS2CL3
81ACTN41
23529CLCF12
11033ADAP11
3845KRAS1
8289ARID1A1
203228C9orf722
84572GNPTG1
151742PPM1L2
6597SMARCA41
29092LINC003391
100270984RPL31P151
4771NF21
10329RXYLT11
23557SNAPIN2
3694ITGB62
87688RPL7AP501
677822SNORA401
11252PACSIN21
1500CTNND11
7068THRB2
1387CREBBP1
100420300FTH1P231
81563C1orf212
63971KIF13A1
5788PTPRC1
5579PRKCB1
8242KDM5C1
57648KIAA15222
4851NOTCH11
7158TP53BP11
55294FBXW71
8209GATD3A2
4610MYCL1
8086AAAS1
4817NIT11
534ATP6V1G21
154791FMC11
4300MLLT31
286077FAM83H1
695BTK1
54955C1orf1091
2064ERBB23
6850SYK1
284958NT5DC41
5257PHKB1
3728JUP2
100418919TNPO1P12
84985FAM83A1
127687C1orf1224
79751SLC25A221
25771TBC1D22A1
2778GNAS1
472ATM1
8703B4GALT31
3397ID12
27242TNFRSF211
80267EDEM31
2050EPHB42
3783KCNN42
1029CDKN2A2
9361LONP11
2868GRK41
1729DIAPH11
10018BCL2L111
2501FTH1P82
27347STK391
7157TP531
6794STK111
3791KDR1
4292MLH11
254427PROSER21
85439STON21
8796SCEL2
55902ACSS21
64115VSIR2
7495XBP1P11
9046DOK21
162979ZNF2962
100151652RNU7-57P1
138716RPP25L1
57111RAB251
4089SMAD41
4778NFE21
64092SAMSN12
1512CTSH1
5290PIK3CA2
51586MED151
8674VAMP41
1956EGFR1
4609MYC1
6812STXBP11
5155PDGFB1
85369STRIP11
92400RBM182
388695LYSMD12
1031CDKN2C1
26823RNU12-2P1
5029P2RY21
673BRAF1
2162F13A11
652995UCA14
79829NAA401
8651SOCS11
5728PTEN1
79722ANKRD551
161436EML51
54539NDUFB111
1951CELSR32
90701SEC11C1
7052TGM24
83596BCL2L121
255031LINC009572
9749PHACTR21
94032CAMK2N22
6533SLC6A61
1493CTLA41
201798TIGD42
7248TSC11
5169ENPP31
80223RAB11FIP12
26059ERC21
57142RTN41
4772NFATC11
221711SYCP2L1
9894TELO21
1825DSC31
5925RB11
4893NRAS2
84872ZC3H102
7403KDM6A1
57198ATP8B22
25912C1orf431
60677CELF61
9570GOSR21
84079ANKRD271
100141515C17orf991
595CCND11
4763NF11
4613MYCN1
201294UNC13D1
51665ASB11
2497FTH1P21
1499CTNNB11
399687MYO18A1
5624PROC1

Gene in drug-gene network: Network Plot

Models in Saracatinib

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