iGMDRD409
| Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
| Saracatinib | CHEMBL217092 | 10302500 | DB11805 | Alone | Small Molecule |
Drug Class:
Antineoplastic AgentsDioxolesEnzyme InhibitorsHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHeterocyclic Compounds, 2-RingKinase inhibitorDrug Pathways:
RTK signalingDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 100271218 | RPL7P36 | 1 |
| 223 | ALDH9A1 | 1 |
| 400954 | EML6 | 2 |
| 7514 | XPO1 | 1 |
| 84264 | HAGHL | 1 |
| 259173 | ALS2CL | 3 |
| 81 | ACTN4 | 1 |
| 23529 | CLCF1 | 2 |
| 11033 | ADAP1 | 1 |
| 3845 | KRAS | 1 |
| 8289 | ARID1A | 1 |
| 203228 | C9orf72 | 2 |
| 84572 | GNPTG | 1 |
| 151742 | PPM1L | 2 |
| 6597 | SMARCA4 | 1 |
| 29092 | LINC00339 | 1 |
| 100270984 | RPL31P15 | 1 |
| 4771 | NF2 | 1 |
| 10329 | RXYLT1 | 1 |
| 23557 | SNAPIN | 2 |
| 3694 | ITGB6 | 2 |
| 87688 | RPL7AP50 | 1 |
| 677822 | SNORA40 | 1 |
| 11252 | PACSIN2 | 1 |
| 1500 | CTNND1 | 1 |
| 7068 | THRB | 2 |
| 1387 | CREBBP | 1 |
| 100420300 | FTH1P23 | 1 |
| 81563 | C1orf21 | 2 |
| 63971 | KIF13A | 1 |
| 5788 | PTPRC | 1 |
| 5579 | PRKCB | 1 |
| 8242 | KDM5C | 1 |
| 57648 | KIAA1522 | 2 |
| 4851 | NOTCH1 | 1 |
| 7158 | TP53BP1 | 1 |
| 55294 | FBXW7 | 1 |
| 8209 | GATD3A | 2 |
| 4610 | MYCL | 1 |
| 8086 | AAAS | 1 |
| 4817 | NIT1 | 1 |
| 534 | ATP6V1G2 | 1 |
| 154791 | FMC1 | 1 |
| 4300 | MLLT3 | 1 |
| 286077 | FAM83H | 1 |
| 695 | BTK | 1 |
| 54955 | C1orf109 | 1 |
| 2064 | ERBB2 | 3 |
| 6850 | SYK | 1 |
| 284958 | NT5DC4 | 1 |
| 5257 | PHKB | 1 |
| 3728 | JUP | 2 |
| 100418919 | TNPO1P1 | 2 |
| 84985 | FAM83A | 1 |
| 127687 | C1orf122 | 4 |
| 79751 | SLC25A22 | 1 |
| 25771 | TBC1D22A | 1 |
| 2778 | GNAS | 1 |
| 472 | ATM | 1 |
| 8703 | B4GALT3 | 1 |
| 3397 | ID1 | 2 |
| 27242 | TNFRSF21 | 1 |
| 80267 | EDEM3 | 1 |
| 2050 | EPHB4 | 2 |
| 3783 | KCNN4 | 2 |
| 1029 | CDKN2A | 2 |
| 9361 | LONP1 | 1 |
| 2868 | GRK4 | 1 |
| 1729 | DIAPH1 | 1 |
| 10018 | BCL2L11 | 1 |
| 2501 | FTH1P8 | 2 |
| 27347 | STK39 | 1 |
| 7157 | TP53 | 1 |
| 6794 | STK11 | 1 |
| 3791 | KDR | 1 |
| 4292 | MLH1 | 1 |
| 254427 | PROSER2 | 1 |
| 85439 | STON2 | 1 |
| 8796 | SCEL | 2 |
| 55902 | ACSS2 | 1 |
| 64115 | VSIR | 2 |
| 7495 | XBP1P1 | 1 |
| 9046 | DOK2 | 1 |
| 162979 | ZNF296 | 2 |
| 100151652 | RNU7-57P | 1 |
| 138716 | RPP25L | 1 |
| 57111 | RAB25 | 1 |
| 4089 | SMAD4 | 1 |
| 4778 | NFE2 | 1 |
| 64092 | SAMSN1 | 2 |
| 1512 | CTSH | 1 |
| 5290 | PIK3CA | 2 |
| 51586 | MED15 | 1 |
| 8674 | VAMP4 | 1 |
| 1956 | EGFR | 1 |
| 4609 | MYC | 1 |
| 6812 | STXBP1 | 1 |
| 5155 | PDGFB | 1 |
| 85369 | STRIP1 | 1 |
| 92400 | RBM18 | 2 |
| 388695 | LYSMD1 | 2 |
| 1031 | CDKN2C | 1 |
| 26823 | RNU12-2P | 1 |
| 5029 | P2RY2 | 1 |
| 673 | BRAF | 1 |
| 2162 | F13A1 | 1 |
| 652995 | UCA1 | 4 |
| 79829 | NAA40 | 1 |
| 8651 | SOCS1 | 1 |
| 5728 | PTEN | 1 |
| 79722 | ANKRD55 | 1 |
| 161436 | EML5 | 1 |
| 54539 | NDUFB11 | 1 |
| 1951 | CELSR3 | 2 |
| 90701 | SEC11C | 1 |
| 7052 | TGM2 | 4 |
| 83596 | BCL2L12 | 1 |
| 255031 | LINC00957 | 2 |
| 9749 | PHACTR2 | 1 |
| 94032 | CAMK2N2 | 2 |
| 6533 | SLC6A6 | 1 |
| 1493 | CTLA4 | 1 |
| 201798 | TIGD4 | 2 |
| 7248 | TSC1 | 1 |
| 5169 | ENPP3 | 1 |
| 80223 | RAB11FIP1 | 2 |
| 26059 | ERC2 | 1 |
| 57142 | RTN4 | 1 |
| 4772 | NFATC1 | 1 |
| 221711 | SYCP2L | 1 |
| 9894 | TELO2 | 1 |
| 1825 | DSC3 | 1 |
| 5925 | RB1 | 1 |
| 4893 | NRAS | 2 |
| 84872 | ZC3H10 | 2 |
| 7403 | KDM6A | 1 |
| 57198 | ATP8B2 | 2 |
| 25912 | C1orf43 | 1 |
| 60677 | CELF6 | 1 |
| 9570 | GOSR2 | 1 |
| 84079 | ANKRD27 | 1 |
| 100141515 | C17orf99 | 1 |
| 595 | CCND1 | 1 |
| 4763 | NF1 | 1 |
| 4613 | MYCN | 1 |
| 201294 | UNC13D | 1 |
| 51665 | ASB1 | 1 |
| 2497 | FTH1P2 | 1 |
| 1499 | CTNNB1 | 1 |
| 399687 | MYO18A | 1 |
| 5624 | PROC | 1 |
Gene in drug-gene network: Network Plot
Models in Saracatinib
CLASSFICATION
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