ERC2
Summary: This gene encodes a protein that belongs to the Rab3-interacting molecule (RIM)-binding protein family. Members of this protein family form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ELKS/RAB6-interacting/CAST family member 2 | MIM:617250 | Ensembl:ENSG00000187672 | HGNC:HGNC:31922 | PA162385249 | 3p14.3 |
GO terms in ERC2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005856 | cytoskeleton |
| CC | IEA | GO:0030054 | cell junction |
| CC | ISS | GO:0030426 | growth cone |
| CC | ISS | GO:0042734 | presynaptic membrane |
| CC | TAS | GO:0048786 | presynaptic active zone |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: ERC2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ERC2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP410 | Exercise-induced Circadian Regulation |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ERC2
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.