CELF6
Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| CUGBP Elav-like family member 6 | MIM:612681 | Ensembl:ENSG00000140488 | HGNC:HGNC:14059 | PA25430 | 15q23 |
GO terms in CELF6
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0003723 | RNA binding |
| MF | NAS | GO:0003723 | RNA binding |
| MF | IBA | GO:0003729 | mRNA binding |
| CC | IBA | GO:0005634 | nucleus |
| CC | NAS | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | NAS | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005829 | cytosol |
| BP | IBA | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome |
| BP | IDA | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome |
| BP | IBA | GO:0006376 | mRNA splice site selection |
| BP | IEA | GO:0006397 | mRNA processing |
Gene expression in normal tissue: CELF6
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CELF6
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CELF6
CLASSFICATION
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