CELF6
Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:612681 Ensembl IDEnsembl:ENSG00000140488 HGNC IDHGNC:HGNC:14059 PHARMGKB IDPA25430 Map Location15q23 | |||||
GO terms in CELF6
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0003723 | RNA binding |
| MF | NAS | GO:0003723 | RNA binding |
| MF | IBA | GO:0003729 | mRNA binding |
| CC | IBA | GO:0005634 | nucleus |
| CC | NAS | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
Gene expression in normal tissue: CELF6
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CELF6
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD409 | Saracatinib | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CELF6
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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