SAMSN1
Summary: SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| SAM domain, SH3 domain and nuclear localization signals 1 | MIM:607978 | Ensembl:ENSG00000155307 | HGNC:HGNC:10528 | PA34939 | 21q11.2 |
GO terms in SAMSN1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0001784 | phosphotyrosine residue binding |
| MF | IDA | GO:0001784 | phosphotyrosine residue binding |
| MF | HDA | GO:0003723 | RNA binding |
| BP | ISS | GO:0002820 | negative regulation of adaptive immune response |
| BP | IBA | GO:0009966 | regulation of signal transduction |
| BP | IBA | GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation |
| BP | ISS | GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation |
| BP | IBA | GO:0050869 | negative regulation of B cell activation |
| BP | ISS | GO:0050869 | negative regulation of B cell activation |
| CC | IEA | GO:0001726 | ruffle |
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005829 | cytosol |
| CC | IDA | GO:0005886 | plasma membrane |
Gene expression in normal tissue: SAMSN1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SAMSN1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2512 | Integrated Lung Cancer Pathway |
| wikipathways | WP3945 | TYROBP Causal Network |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SAMSN1
CLASSFICATION
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