SAMSN1

Summary: SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameSAM domain, SH3 domain and nuclear localization signals 1
OMIM IDMIM:607978
Ensembl IDEnsembl:ENSG00000155307
HGNC IDHGNC:HGNC:10528
PHARMGKB IDPA34939
Map Location21q11.2

GO terms in SAMSN1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0001784 phosphotyrosine residue binding
MF IDA GO:0001784 phosphotyrosine residue binding
MF HDA GO:0003723 RNA binding
BP ISS GO:0002820 negative regulation of adaptive immune response
BP IBA GO:0009966 regulation of signal transduction
BP IBA GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
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Gene expression in normal tissue: SAMSN1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

RTK signaling1

Pathways in SAMSN1


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Database
Pathway ID
Pathway Des.
wikipathways WP2512 Integrated Lung Cancer Pathway
wikipathways WP3945 TYROBP Causal Network
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD409 Saracatinib 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SAMSN1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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