MYCL

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameMYCL proto-oncogene, bHLH transcription factor
OMIM IDMIM:164850
Ensembl IDEnsembl:ENSG00000116990
HGNC IDHGNC:HGNC:7555
PHARMGKB IDPA31355
Map Location1p34.2

Gene Categories:

CLINICALLY ACTIONABLE

GO terms in MYCL


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Term Type
Evidence Type
GO Term ID
GO Des.
MF ISA GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF ISM GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF NAS GO:0003677 DNA binding
MF TAS GO:0003677 DNA binding
MF IEA GO:0046983 protein dimerization activity
CC IDA GO:0005634 nucleus
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Gene expression in normal tissue: MYCL

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined45ERK MAPK signaling4RTK signaling4Apoptosis regulation3Protein stability and degradation2EGFR signaling1Other, kinases1Insulin signaling pathway1Biosynthesis of secondary metabolites1Mitosis1

Pathways in MYCL


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD889 Compound 7d-cis 10
iGMDRD409 Saracatinib 1
iGMDRD546 BMS-754807 3
iGMDRD427 ABT737 8
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MYCL

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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