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iGMDRD213

Canonical SMILES: CC1=CC(=C(N1CC2=CC=CC=C2)C)C(=O)CN3C(=O)CCC3=O

InChI: InChI=1S/C19H20N2O3/c1-13-10-16(17(22)12-21-18(23)8-9-19(21)24)14(2)20(13)11-15-6-4-3-5-7-15/h3-7,10H,8-9,11-12H2,1-2H3

InChI Key: JRESCQKIRPOOEM-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
SMR000068650	CHEMBL1404553	2113510	Alone	Small Molecule

Drug Targets:

S1PR2

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
6664	SOX11	6
79054	TRPM8	2
10221	TRIB1	3
23085	ERC1	2
132	ADK	6
2339	FNTA	3
9706	ULK2	3
9149	DYRK1B	3
347365	ITIH6	2
4750	NEK1	3
3939	LDHA	2
5934	RBL2	2
2335	FN1	3
79092	CARD14	2
9869	SETDB1	2
843	CASP10	3
9530	BAG4	3
5754	PTK7	2
5079	PAX5	3
4313	MMP2	2
23235	SIK2	5
4170	MCL1	1
22853	LMTK2	2
7253	TSHR	2
23310	NCAPD3	3
9816	URB2	3
577	ADGRB3	2
112858	TP53RK	2
1387	CREBBP	6
5756	TWF1	1
2043	EPHA4	3
5788	PTPRC	3
4881	NPR1	3
5579	PRKCB	6
11200	CHEK2	3
5596	MAPK4	1
7373	COL14A1	2
139378	ADGRG4	2
7158	TP53BP1	3
23522	KAT6B	7
55728	N4BP2	2
4610	MYCL	8
2051	EPHB6	2
3714	JAG2	2
22806	IKZF3	3
6041	RNASEL	2
200576	PIKFYVE	2
6091	ROBO1	2
199699	DAND5	3
51343	FZR1	1
7088	TLE1	3
1277	COL1A1	3
287015	TRIM42	2
54899	PXK	3
7486	WRN	2
23387	SIK3	2
92	ACVR2A	2
1452	CSNK1A1	3
1973	EIF4A1	3
50488	MINK1	3
6098	ROS1	1
9472	AKAP6	2
472	ATM	3
8148	TAF15	3
5924	RASGRF2	2
9564	BCAR1	2
4058	LTK	1
5450	POU2AF1	5
2272	FHIT	4
5863	RGL2	2
1029	CDKN2A	8
7157	TP53	1
8218	CLTCL1	1
114788	CSMD3	1
7249	TSC2	2
65243	ZFP69B	2
1045	CDX2	1
105	ADARB2	2
1102	RCBTB2	1
55437	STRADB	2
2309	FOXO3	2
80205	CHD9	6
57578	UNC79	2
8997	KALRN	3
4437	MSH3	5
170692	ADAMTS18	2
6654	SOS1	3
78989	COLEC11	2
23373	CRTC1	2
285220	EPHA6	4
546	ATRX	1
5297	PI4KA	2
10926	DBF4	4
10535	RNASEH2A	3
64840	PORCN	3
9972	NUP153	3
5290	PIK3CA	4
5366	PMAIP1	3
57154	SMURF1	2
4609	MYC	1
11064	CNTRL	2
90956	ADCK2	3
2624	GATA2	2
90427	BMF	2
283629	TSSK4	3
79759	ZNF668	3
375056	MIA3	2
1544	CYP1A2	6
6872	TAF1	2
673	BRAF	4
84879	MFSD2A	6
22976	PAXIP1	2
23532	PRAME	3
8924	HERC2	1
120892	LRRK2	3
5294	PIK3CG	6
9509	ADAMTS2	3
10010	TANK	2
1487	CTBP1	3
7030	TFE3	3
667	DST	4
7454	WAS	2
7036	TFR2	6
55359	STYK1	3
29959	NRBP1	2
53904	MYO3A	1
9372	ZFYVE9	4
22843	PPM1E	3
1643	DDB2	2
54738	FEV	3
5291	PIK3CB	2
10076	PTPRU	2
57680	CHD8	2
2690	GHR	4
2049	EPHB3	3
6093	ROCK1	3
5335	PLCG1	2
5587	PRKD1	3
55007	FAM118A	2
1719	DHFR	5
57448	BIRC6	3
2157	F8	2
79837	PIP4K2C	2
1030	CDKN2B	5
3984	LIMK1	2
80216	ALPK1	3
201163	FLCN	3
444	ASPH	3
2903	GRIN2A	3
7403	KDM6A	2
2308	FOXO1	3
3716	JAK1	2
142	PARP1	3
57096	RPGRIP1	3
10048	RANBP9	2
4193	MDM2	2
56155	TEX14	2
5590	PRKCZ	2

Gene in drug-gene network: Network Plot

Models in SMR000068650

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DATATYPES

CLASSFICATION

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