ALPK1


Summary: This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:607347
PHARMGKB IDPA134891785
Map Location4q25

GO terms in ALPK1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0005524 ATP binding
BP IEA GO:0006468 protein phosphorylation
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Gene expression in normal tissue: ALPK1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined51Apoptosis regulation2Protein stability and degradation1Drug metabolism - cytochrome P4501DNA replication1Chromatin other1Purine metabolism1Genome integrity1Ferroptosis1p53 pathway1

Pathways in ALPK1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD126 Tipifarnib 5
iGMDRD210 AC55649 2
iGMDRD889 Compound 7d-cis 2
iGMDRD772 BRD4770 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ALPK1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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