ALPK1
Summary: This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| alpha kinase 1 | MIM:607347 | Ensembl:ENSG00000073331 | HGNC:HGNC:20917 | PA134891785 | 4q25 |
GO terms in ALPK1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0005524 | ATP binding |
| BP | IEA | GO:0006468 | protein phosphorylation |
Gene expression in normal tissue: ALPK1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ALPK1
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD126 | Tipifarnib | 5 |
| iGMDRD210 | AC55649 | 2 |
| iGMDRD889 | Compound 7d-cis | 2 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD425 | ERASTIN | 4 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD579 | PF750 | 2 |
| iGMDRD394 | BX-795 | 1 |
| iGMDRD466 | Chaetocin | 1 |
| iGMDRD280 | CYTOCHALASIN B | 2 |
| iGMDRD634 | SCHEMBL2608041 | 2 |
| iGMDRD375 | GW-405833 | 2 |
| iGMDRD639 | YK 4-279 | 1 |
| iGMDRD316 | N9-Isopropyl-olomoucine | 4 |
| iGMDRD793 | BEC (hydrochloride) | 1 |
| iGMDRD193 | Fqi1 | 3 |
| iGMDRD163 | all trans Retinoic Acid | 4 |
| iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 2 |
| iGMDRD318 | PAC-1 | 1 |
| iGMDRD187 | BRD9876 | 3 |
| iGMDRD870 | BRD63610 | 3 |
| iGMDRD690 | PRIMA-1MET | 5 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD369 | TGX-115 | 1 |
| iGMDRD356 | PNU-74654 | 3 |
| iGMDRD268 | Cerulenin | 5 |
| iGMDRD598 | QS-11 | 3 |
| iGMDRD451 | Serdemetan | 5 |
| iGMDRD74 | Idarubicin | 1 |
| iGMDRD399 | Selumetinib | 1 |
| iGMDRD730 | Kahalalide F | 1 |
| iGMDRD780 | PP-30 | 4 |
| iGMDRD398 | Sepantronium | 1 |
| iGMDRD116 | CD437 | 1 |
| iGMDRD532 | Olaparib | 5 |
| iGMDRD560 | MK-2206 | 4 |
| iGMDRD424 | Tamatinib | 1 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 2 |
| iGMDRD79 | Gemcitabine | 3 |
| iGMDRD701 | NVP-AUY922 | 1 |
| iGMDRD307 | Manumycin A | 4 |
| iGMDRD512 | nutlin 3 | 2 |
| iGMDRD148 | Pifithrin-mu | 1 |
| iGMDRD248 | BRD4354 | 1 |
| iGMDRD123 | Isoevodiamine | 3 |
| iGMDRD945 | ML214 | 3 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 3 |
| iGMDRD85 | Ursolic acid | 2 |
| iGMDRD221 | Tamoxifen | 2 |
| iGMDRD6 | AM-580 | 4 |
| iGMDRD192 | CIL56 | 3 |
| iGMDRD415 | LE-135 | 1 |
| iGMDRD77 | Itraconazole | 2 |
| iGMDRD213 | SMR000068650 | 3 |
| iGMDRD158 | NSC141540 | 3 |
| iGMDRD220 | fumonisin B1 | 3 |
| iGMDRD137 | Indisulam | 5 |
| iGMDRD147 | Prima-1 | 3 |
| iGMDRD246 | NPC26 | 1 |
| iGMDRD367 | Ro 28-1675 | 1 |
| iGMDRD329 | Merck60 | 3 |
| iGMDRD662 | JQ-1 | 2 |
| iGMDRD269 | Purmorphamine | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ALPK1
CLASSFICATION
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