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iGMDRD269

Canonical SMILES: C1CCC(CC1)N2C=NC3=C2N=C(N=C3NC4=CC=C(C=C4)N5CCOCC5)OC6=CC=CC7=CC=CC=C76

InChI: InChI=1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)

InChI Key: FYBHCRQFSFYWPY-UHFFFAOYSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
Purmorphamine	5284330	Alone	Small Molecule

Drug Targets:

SMO

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
132	ADK	2
5933	RBL1	2
7161	TP73	3
5546	PRCC	1
3708	ITPR1	1
7272	TTK	2
8289	ARID1A	2
80070	ADAMTS20	1
5934	RBL2	2
1263	PLK3	2
6597	SMARCA4	2
7444	VRK2	2
23235	SIK2	4
10863	ADAM28	2
1404	HAPLN1	2
9232	PTTG1	3
5467	PPARD	3
3456	IFNB1	2
5465	PPARA	3
8784	TNFRSF18	2
5664	PSEN2	3
342667	STAC2	3
5900	RALGDS	3
80129	CCDC170	1
51804	SIX4	1
8643	PTCH2	2
23191	CYFIP1	1
29760	BLNK	3
158056	MAMDC4	2
10087	COL4A3BP	1
659	BMPR2	2
9472	AKAP6	1
5165	PDK3	3
139285	AMER1	2
4058	LTK	3
5450	POU2AF1	4
9794	MAML1	3
83694	RPS6KL1	1
3236	HOXD10	2
11143	KAT7	2
7704	ZBTB16	2
2322	FLT3	3
8218	CLTCL1	2
65243	ZFP69B	2
984	CDK11B	1
6280	S100A9	3
2668	GDNF	3
4139	MARK1	2
5606	MAP2K3	1
7043	TGFB3	1
100130933	SMIM6	3
29951	PDZRN4	1
2189	FANCG	3
5156	PDGFRA	2
673	BRAF	2
4790	NFKB1	1
83452	RAB33B	1
2078	ERG	1
867	CBL	2
9451	EIF2AK3	2
9509	ADAMTS2	3
23476	BRD4	2
5728	PTEN	1
667	DST	2
284086	NEK8	2
6146	RPL22	2
79834	PEAK1	2
7465	WEE1	3
558	AXL	1
5581	PRKCE	3
2690	GHR	1
8031	NCOA4	1
53353	LRP1B	1
7293	TNFRSF4	5
54101	RIPK4	2
4067	LYN	2
80216	ALPK1	1
2122	MECOM	2
4217	MAP3K5	2
5586	PKN2	1
10494	STK25	2
11086	ADAM29	3
581	BAX	1
4763	NF1	1
5260	PHKG1	1
23683	PRKD3	3
3679	ITGA7	2
1436	CSF1R	1
2886	GRB7	3

Gene in drug-gene network: Network Plot

Models in Purmorphamine

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.