HAPLN1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| hyaluronan and proteoglycan link protein 1 | MIM:115435 | Ensembl:ENSG00000145681 | HGNC:HGNC:2380 | PA26901 | 5q14.3 |
Gene Categories:
DRUGGABLE GENOMEGO terms in HAPLN1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0030021 | extracellular matrix structural constituent conferring compression resistance |
| BP | IBA | GO:0001501 | skeletal system development |
| BP | IEA | GO:0007155 | cell adhesion |
| BP | IBA | GO:0007417 | central nervous system development |
| BP | TAS | GO:0030198 | extracellular matrix organization |
| CC | TAS | GO:0005576 | extracellular region |
| CC | TAS | GO:0031012 | extracellular matrix |
| CC | HDA | GO:0062023 | collagen-containing extracellular matrix |
| CC | HDA | GO:0062023 | collagen-containing extracellular matrix |
Gene expression in normal tissue: HAPLN1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HAPLN1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1474244 | Extracellular matrix organization |
| reactome | R-HSA-3000178 | ECM proteoglycans |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD150 | RITA | 2 |
| iGMDRD560 | MK-2206 | 3 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD462 | OSI-906 (Linsitinib) | 1 |
| iGMDRD126 | Tipifarnib | 2 |
| iGMDRD151 | CHM-1 | 3 |
| iGMDRD330 | BRD4132 | 1 |
| iGMDRD599 | Salermide | 6 |
| iGMDRD579 | PF750 | 2 |
| iGMDRD1008 | SR-II-138A | 2 |
| iGMDRD420 | Leucascandrolide A | 3 |
| iGMDRD123 | Isoevodiamine | 6 |
| iGMDRD154 | NSC23766 | 4 |
| iGMDRD446 | LY 2183240 | 4 |
| iGMDRD85 | Ursolic acid | 3 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD193 | Fqi1 | 5 |
| iGMDRD103 | SN-38 | 2 |
| iGMDRD138 | PX 12 | 2 |
| iGMDRD260 | FQI-2 | 4 |
| iGMDRD5 | Tyrphostin AG 1478 | 3 |
| iGMDRD300 | Tozasertib | 2 |
| iGMDRD64 | Parbendazole | 5 |
| iGMDRD356 | PNU-74654 | 2 |
| iGMDRD100 | Zebularine | 2 |
| iGMDRD399 | Selumetinib | 2 |
| iGMDRD506 | Fedratinib | 3 |
| iGMDRD269 | Purmorphamine | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in HAPLN1
CLASSFICATION
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