iGMDRD462
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| OSI-906 (Linsitinib) | CHEMBL1091644 | 11640400 | Alone | Small Molecule |
Drug Pathways:
IGFR signalingDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 8241 | RBM10 | 1 |
| 2956 | MSH6 | 1 |
| 3845 | KRAS | 3 |
| 3757 | KCNH2 | 1 |
| 55215 | FANCI | 1 |
| 8289 | ARID1A | 1 |
| 6597 | SMARCA4 | 1 |
| 9869 | SETDB1 | 1 |
| 83481 | EPPK1 | 1 |
| 23235 | SIK2 | 1 |
| 4170 | MCL1 | 3 |
| 1404 | HAPLN1 | 1 |
| 9611 | NCOR1 | 1 |
| 8242 | KDM5C | 1 |
| 5159 | PDGFRB | 1 |
| 4851 | NOTCH1 | 3 |
| 2033 | EP300 | 1 |
| 54477 | PLEKHA5 | 1 |
| 27065 | NSG1 | 1 |
| 4301 | AFDN | 1 |
| 25937 | WWTR1 | 1 |
| 7416 | VDAC1 | 1 |
| 2210 | FCGR1B | 1 |
| 6850 | SYK | 1 |
| 659 | BMPR2 | 1 |
| 3667 | IRS1 | 1 |
| 10413 | YAP1 | 1 |
| 1029 | CDKN2A | 2 |
| 10018 | BCL2L11 | 1 |
| 5834 | PYGB | 1 |
| 4088 | SMAD3 | 1 |
| 3673 | ITGA2 | 1 |
| 25836 | NIPBL | 2 |
| 3791 | KDR | 1 |
| 4086 | SMAD1 | 1 |
| 7422 | VEGFA | 1 |
| 3481 | IGF2 | 2 |
| 84181 | CHD6 | 2 |
| 4904 | YBX1 | 1 |
| 57111 | RAB25 | 1 |
| 5290 | PIK3CA | 1 |
| 675 | BRCA2 | 1 |
| 607 | BCL9 | 1 |
| 1956 | EGFR | 1 |
| 54206 | ERRFI1 | 1 |
| 8682 | PEA15 | 1 |
| 896 | CCND3 | 1 |
| 3553 | IL1B | 1 |
| 5781 | PTPN11 | 1 |
| 10752 | CHL1 | 1 |
| 5728 | PTEN | 2 |
| 7385 | UQCRC2 | 1 |
| 9748 | SLK | 1 |
| 1030 | CDKN2B | 1 |
| 100862685 | ERVK-19 | 1 |
| 5054 | SERPINE1 | 1 |
| 196528 | ARID2 | 1 |
| 8661 | EIF3A | 1 |
| 142 | PARP1 | 1 |
| 84446 | BRSK1 | 1 |
| 4763 | NF1 | 2 |
| 4613 | MYCN | 1 |
| 55193 | PBRM1 | 1 |
Gene in drug-gene network: Network Plot
Models in OSI-906 (Linsitinib)
CLASSFICATION
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