PLEKHA5
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| pleckstrin homology domain containing A5 | MIM:607770 | Ensembl:ENSG00000052126 | HGNC:HGNC:30036 | PA134949896 | 12p12.3 |
GO terms in PLEKHA5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | ND | GO:0008150 | biological_process |
| BP | IEA | GO:0061458 | reproductive system development |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005829 | cytosol |
| CC | HDA | GO:0016020 | membrane |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0010314 | phosphatidylinositol-5-phosphate binding |
| MF | IEA | GO:0032266 | phosphatidylinositol-3-phosphate binding |
| MF | IEA | GO:0070273 | phosphatidylinositol-4-phosphate binding |
| MF | IEA | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding |
Gene expression in normal tissue: PLEKHA5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PLEKHA5
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| netpath | Pathway_EGFR1 | EGFR1 |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1483255 | PI Metabolism |
| reactome | R-HSA-1483257 | Phospholipid metabolism |
| reactome | R-HSA-1660499 | Synthesis of PIPs at the plasma membrane |
| reactome | R-HSA-556833 | Metabolism of lipids |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD322 | FK 866 | 4 |
| iGMDRD263 | AACOCF3 | 4 |
| iGMDRD552 | AZD-1775 | 2 |
| iGMDRD246 | NPC26 | 4 |
| iGMDRD505 | Pevonedistat | 5 |
| iGMDRD366 | PI-103 | 2 |
| iGMDRD286 | Nsc 632839 | 7 |
| iGMDRD414 | MST-312 | 2 |
| iGMDRD434 | BMS-536924 | 2 |
| iGMDRD705 | Nakiterpiosin | 4 |
| iGMDRD289 | Parthenolide | 4 |
| iGMDRD137 | Indisulam | 2 |
| iGMDRD158 | NSC141540 | 2 |
| iGMDRD121 | GMX1778 | 2 |
| iGMDRD103 | SN-38 | 3 |
| iGMDRD883 | CIL55A | 2 |
| iGMDRD945 | ML214 | 4 |
| iGMDRD123 | Isoevodiamine | 3 |
| iGMDRD177 | Teniposide | 2 |
| iGMDRD237 | ABT-751 | 5 |
| iGMDRD351 | GW843682X | 1 |
| iGMDRD314 | Tanespimycin | 1 |
| iGMDRD49 | Mitomycin | 2 |
| iGMDRD341 | Triacsin c | 2 |
| iGMDRD701 | NVP-AUY922 | 4 |
| iGMDRD79 | Gemcitabine | 2 |
| iGMDRD116 | CD437 | 3 |
| iGMDRD150 | RITA | 1 |
| iGMDRD512 | nutlin 3 | 3 |
| iGMDRD356 | PNU-74654 | 1 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD399 | Selumetinib | 1 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD100 | Zebularine | 3 |
| iGMDRD870 | BRD63610 | 1 |
| iGMDRD255 | SB225002 | 3 |
| iGMDRD260 | FQI-2 | 2 |
| iGMDRD138 | PX 12 | 5 |
| iGMDRD474 | Avrainvillamide | 2 |
| iGMDRD270 | Ciclosporin | 1 |
| iGMDRD466 | Chaetocin | 4 |
| iGMDRD297 | Austocystin D | 1 |
| iGMDRD61 | Kinetin riboside | 1 |
| iGMDRD193 | Fqi1 | 6 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD446 | LY 2183240 | 3 |
| iGMDRD462 | OSI-906 (Linsitinib) | 1 |
| iGMDRD670 | ML 210 | 2 |
| iGMDRD779 | PRL-3 Inhibitor I | 1 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD772 | BRD4770 | 2 |
| iGMDRD420 | Leucascandrolide A | 3 |
| iGMDRD433 | Lexibulin | 4 |
| iGMDRD151 | CHM-1 | 6 |
| iGMDRD126 | Tipifarnib | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PLEKHA5
CLASSFICATION
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