SEARCH

HOME / SEARCH / Chaetocin

iGMDRD466

Canonical SMILES: CN1C(=O)C23CC4(C(N2C(=O)C1(SS3)CO)NC5=CC=CC=C54)C67CC89C(=O)N(C(C(=O)N8C6NC1=CC=CC=C71)(SS9)CO)C

InChI: InChI=1S/C30H28N6O6S4/c1-33-21(39)27-11-25(15-7-3-5-9-17(15)31-19(25)35(27)23(41)29(33,13-37)45-43-27)26-12-28-22(40)34(2)30(14-38,46-44-28)24(42)36(28)20(26)32-18-10-6-4-8-16(18)26/h3-10,19-20,31-32,37-38H,11-14H2,1-2H3/t19-,20-,25+,26+,27+,28+,29+,30+/m1/s1

InChI Key: PZPPOCZWRGNKIR-PNVYSBBASA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
Chaetocin	11657700	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
64901	RANBP17	2
1105	CHD1	3
27125	AFF4	1
4854	NOTCH3	2
8999	CDKL2	2
5027	P2RX7	1
10903	MTMR11	3
471	ATIC	2
79848	CSPP1	2
10221	TRIB1	1
8444	DYRK3	2
6581	SLC22A3	1
132	ADK	1
5933	RBL1	1
8915	BCL10	2
11183	MAP4K5	3
2200	FBN1	1
4303	FOXO4	2
57679	ALS2	3
150465	TTL	3
57554	LRRC7	3
9706	ULK2	1
7272	TTK	3
51347	TAOK3	3
4750	NEK1	2
23552	CDK20	1
8289	ARID1A	1
8573	CASK	2
5934	RBL2	3
6938	TCF12	3
1263	PLK3	2
9475	ROCK2	1
4036	LRP2	3
5133	PDCD1	4
843	CASP10	3
7444	VRK2	2
7942	TFEB	3
390502	SERPINA2	6
5754	PTK7	3
64783	RBM15	6
51684	SUFU	3
4771	NF2	3
10863	ADAM28	2
6598	SMARCB1	3
9891	NUAK1	1
55781	RIOK2	3
23310	NCAPD3	2
2241	FER	2
55534	MAML3	1
5154	PDGFA	3
51199	NIN	2
28231	SLCO4A1	3
1387	CREBBP	2
1893	ECM1	1
5756	TWF1	1
55023	PHIP	3
5467	PPARD	3
5579	PRKCB	5
11200	CHEK2	3
31	ACACA	2
1602	DACH1	3
51755	CDK12	5
9411	ARHGAP29	4
3604	TNFRSF9	4
8295	TRRAP	10
6722	SRF	3
5314	PKHD1	2
139378	ADGRG4	3
10295	BCKDK	2
2033	EP300	3
6927	HNF1A	3
641	BLM	2
64324	NSD1	2
23522	KAT6B	5
54477	PLEKHA5	4
2115	ETV1	3
4301	AFDN	3
816	CAMK2B	2
55819	RNF130	3
5900	RALGDS	1
122011	CSNK1A1L	2
3621	ING1	2
4478	MSN	4
1586	CYP17A1	1
6256	RXRA	2
32	ACACB	3
26353	HSPB8	3
22806	IKZF3	1
7416	VDAC1	3
22984	PDCD11	2
200576	PIKFYVE	4
6733	SRPK2	1
6091	ROBO1	2
1050	CEBPA	3
2260	FGFR1	3
10188	TNK2	3
9636	ISG15	3
11169	WDHD1	1
4216	MAP3K4	3
29904	EEF2K	3
51804	SIX4	3
7088	TLE1	2
27324	TOX3	1
284217	LAMA1	3
1143	CHRNB4	2
55681	SCYL2	2
4982	TNFRSF11B	4
238	ALK	2
1277	COL1A1	1
2064	ERBB2	8
6850	SYK	2
287015	TRIM42	3
65217	PCDH15	5
8395	PIP5K1B	4
6663	SOX10	3
23191	CYFIP1	3
9759	HDAC4	2
92	ACVR2A	2
8215	DVL1P1	3
10087	COL4A3BP	3
6464	SHC1	5
659	BMPR2	2
6098	ROS1	1
2778	GNAS	1
3667	IRS1	2
80243	PREX2	2
472	ATM	5
5165	PDK3	3
575	ADGRB1	1
5924	RASGRF2	1
2734	GLG1	3
4058	LTK	3
1123	CHN1	3
7010	TEK	1
5289	PIK3C3	2
898	CCNE1	1
23152	CIC	3
2272	FHIT	4
7867	MAPKAPK3	3
10290	SPEG	2
7184	HSP90B1	3
10062	NR1H3	3
9794	MAML1	3
5129	CDK18	3
27436	EML4	2
57523	NYNRIN	3
83694	RPS6KL1	6
2868	GRK4	2
9874	TLK1	3
58508	KMT2C	2
2099	ESR1	2
6092	ROBO2	2
4173	MCM4	4
4855	NOTCH4	1
6794	STK11	4
25836	NIPBL	2
7869	SEMA3B	4
8218	CLTCL1	5
57410	SCYL1	3
836	CASP3	2
2329	FMO4	3
4292	MLH1	2
2133	EXT3	1
9639	ARHGEF10	1
7249	TSC2	8
1019	CDK4	3
7409	VAV1	3
65243	ZFP69B	3
8874	ARHGEF7	2
1555	CYP2B6	2
5597	MAPK6	2
7038	TG	2
6197	RPS6KA3	3
65125	WNK1	1
652	BMP4	2
5650	KLK7	2
7175	TPR	2
80205	CHD9	4
2000	ELF4	3
57578	UNC79	4
8997	KALRN	5
23469	PHF3	3
170692	ADAMTS18	3
6654	SOS1	2
78989	COLEC11	3
23373	CRTC1	2
285220	EPHA6	2
546	ATRX	1
51366	UBR5	1
3426	CFI	1
3417	IDH1	3
5606	MAP2K3	6
5297	PI4KA	1
7786	MAP3K12	1
10926	DBF4	1
10535	RNASEH2A	2
57144	PAK5	2
3702	ITK	2
2187	FANCB	3
5290	PIK3CA	1
6046	BRD2	3
5034	P4HB	4
26524	LATS2	1
90	ACVR1	2
7043	TGFB3	3
2318	FLNC	2
64919	BCL11B	1
675	BRCA2	4
607	BCL9	3
7075	TIE1	3
1956	EGFR	1
8445	DYRK2	1
640	BLK	2
157680	VPS13B	2
4609	MYC	3
90956	ADCK2	1
2624	GATA2	3
5155	PDGFB	3
10461	MERTK	3
100130933	SMIM6	3
283629	TSSK4	3
5663	PSEN1	2
79759	ZNF668	3
3635	INPP5D	2
375056	MIA3	3
137872	ADHFE1	3
27330	RPS6KA6	4
7153	TOP2A	3
1981	EIF4G1	2
4790	NFKB1	3
6011	GRK1	2
22976	PAXIP1	4
4863	NPAT	3
83452	RAB33B	3
8924	HERC2	3
120892	LRRK2	11
7027	TFDP1	3
6095	RORA	1
57507	ZNF608	1
7468	NSD2	3
8178	ELL	3
9321	TRIP11	3
9843	HEPH	1
8491	MAP4K3	3
5563	PRKAA2	2
23396	PIP5K1C	2
23049	SMG1	2
8312	AXIN1	4
57521	RPTOR	2
208	AKT2	3
7155	TOP2B	3
80124	VCPIP1	3
667	DST	1
7273	TTN	3
91807	MYLK3	1
79834	PEAK1	2
5582	PRKCG	1
55359	STYK1	1
29959	NRBP1	2
53904	MYO3A	3
8648	NCOA1	3
84930	MASTL	3
8805	TRIM24	3
2353	FOS	2
4297	KMT2A	2
10076	PTPRU	2
558	AXL	4
126792	B3GALT6	2
9748	SLK	1
4619	MYH1	2
2932	GSK3B	3
57680	CHD8	2
5923	RASGRF1	4
2690	GHR	3
9223	MAGI1	3
778	CACNA1F	3
1281	COL3A1	1
9659	PDE4DIP	2
63976	PRDM16	2
3557	IL1RN	3
2194	FASN	3
5927	KDM5A	5
5587	PRKD1	2
1719	DHFR	1
5589	PRKCSH	3
1975	EIF4B	3
23139	MAST2	2
2157	F8	1
6778	STAT6	4
4221	MEN1	3
3984	LIMK1	2
6777	STAT5B	2
80216	ALPK1	1
7112	TMPO	3
4261	CIITA	2
170685	NUDT10	3
444	ASPH	2
2122	MECOM	4
51167	CYB5R4	4
1760	DMPK	3
3815	KIT	3
9894	TELO2	3
2903	GRIN2A	2
5925	RB1	3
2065	ERBB3	2
7403	KDM6A	5
7508	XPC	1
4615	MYD88	3
4638	MYLK	5
255239	ANKK1	2
5586	PKN2	3
50964	SOST	3
10494	STK25	4
11086	ADAM29	4
374	AREG	1
79577	CDC73	3
84446	BRSK1	1
1013	CDH15	3
4763	NF1	3
57697	FANCM	6
5260	PHKG1	3
55791	LRIF1	2
1994	ELAVL1	3
10891	PPARGC1A	5
94	ACVRL1	2
2044	EPHA5	2
4629	MYH11	1
23683	PRKD3	1
27255	CNTN6	3
1499	CTNNB1	4
2444	FRK	2
5602	MAPK10	4
2886	GRB7	3
1488	CTBP2	4

Gene in drug-gene network: Network Plot

Models in Chaetocin

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.