SLCO4A1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| solute carrier organic anion transporter family member 4A1 | MIM:612436 | Ensembl:ENSG00000101187 | HGNC:HGNC:10953 | PA35838 | 20q13.33 |
GO terms in SLCO4A1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0015347 | sodium-independent organic anion transmembrane transporter activity |
| MF | IBA | GO:0015349 | thyroid hormone transmembrane transporter activity |
| MF | TAS | GO:0015349 | thyroid hormone transmembrane transporter activity |
| BP | IBA | GO:0043252 | sodium-independent organic anion transport |
| BP | TAS | GO:0043252 | sodium-independent organic anion transport |
| BP | IEA | GO:0055085 | transmembrane transport |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IBA | GO:0005887 | integral component of plasma membrane |
Gene expression in normal tissue: SLCO4A1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SLCO4A1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-382551 | Transport of small molecules |
| reactome | R-HSA-425397 | Transport of vitamins, nucleosides, and related molecules |
| reactome | R-HSA-425407 | SLC-mediated transmembrane transport |
| reactome | R-HSA-879518 | Transport of organic anions |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD137 | Indisulam | 3 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD103 | SN-38 | 2 |
| iGMDRD870 | BRD63610 | 5 |
| iGMDRD267 | Oligomycin A | 3 |
| iGMDRD171 | Pemetrexed | 3 |
| iGMDRD434 | BMS-536924 | 2 |
| iGMDRD705 | Nakiterpiosin | 2 |
| iGMDRD562 | Navitoclax | 2 |
| iGMDRD577 | BIX01294 | 2 |
| iGMDRD872 | BRD7137 | 2 |
| iGMDRD286 | Nsc 632839 | 2 |
| iGMDRD188 | Piperlongumine | 2 |
| iGMDRD451 | Serdemetan | 2 |
| iGMDRD420 | Leucascandrolide A | 3 |
| iGMDRD512 | nutlin 3 | 1 |
| iGMDRD151 | CHM-1 | 3 |
| iGMDRD781 | Sirolimus | 3 |
| iGMDRD560 | MK-2206 | 3 |
| iGMDRD57 | Chloropentafluorobenzene | 3 |
| iGMDRD351 | GW843682X | 2 |
| iGMDRD466 | Chaetocin | 3 |
| iGMDRD297 | Austocystin D | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SLCO4A1
CLASSFICATION
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