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iGMDRD297

Canonical SMILES: CC(C)(CCC1=C2C(=C(C=C1)O)C(=O)C3=C(C4=C(C=C3O2)OC5C4(C=CO5)O)O)O

InChI: InChI=1S/C22H20O8/c1-21(2,26)6-5-10-3-4-11(23)14-17(24)15-12(29-19(10)14)9-13-16(18(15)25)22(27)7-8-28-20(22)30-13/h3-4,7-9,20,23,25-27H,5-6H2,1-2H3/t20-,22-/m1/s1

InChI Key: VXTQFTUOAJRUDO-IFMALSPDSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
Austocystin D	5470400	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
3696	ITGB8	2
10460	TACC3	2
5027	P2RX7	2
3159	HMGA1	3
997	CDC34	3
79054	TRPM8	2
23085	ERC1	2
10987	COPS5	4
21	ABCA3	2
6581	SLC22A3	2
4751	NEK2	3
3383	ICAM1	5
6195	RPS6KA1	1
8476	CDC42BPA	2
7750	ZMYM2	2
4926	NUMA1	4
4066	LYL1	3
5546	PRCC	2
8929	PHOX2B	3
10806	SDCCAG8	3
1969	EPHA2	2
7272	TTK	3
347365	ITIH6	2
3845	KRAS	1
3757	KCNH2	4
5295	PIK3R1	1
6756	SSX1	2
701	BUB1B	2
9760	TOX	3
6597	SMARCA4	6
81035	COLEC12	2
3326	HSP90AB1	2
9869	SETDB1	2
3209	HOXA13	2
4094	MAF	3
5754	PTK7	2
51684	SUFU	2
10892	MALT1	1
4313	MMP2	2
1786	DNMT1	2
10863	ADAM28	6
1607	DGKB	2
23213	SULF1	2
3320	HSP90AA1	2
10142	AKAP9	2
7253	TSHR	1
6732	SRPK1	3
27	ABL2	6
341676	NEK5	3
22821	RASA3	5
79934	COQ8B	5
28231	SLCO4A1	2
26039	SS18L1	2
10454	TAB1	3
3727	JUND	3
1859	DYRK1A	3
2984	GUCY2C	3
31	ACACA	2
10178	TENM1	5
29998	BICRA	2
8295	TRRAP	2
10438	C1D	3
11122	PTPRT	6
9024	BRSK2	3
7173	TPO	1
4851	NOTCH1	3
139378	ADGRG4	6
2033	EP300	1
6927	HNF1A	2
9578	CDC42BPB	3
25865	PRKD2	3
7852	CXCR4	3
54477	PLEKHA5	1
837	CASP4	4
2115	ETV1	4
55819	RNF130	3
84033	OBSCN	2
25937	WWTR1	1
131096	KCNH8	3
122011	CSNK1A1L	1
57787	MARK4	4
1586	CYP17A1	4
6256	RXRA	3
8852	AKAP4	2
3556	IL1RAP	1
4005	LMO2	2
6041	RNASEL	4
200576	PIKFYVE	3
8313	AXIN2	2
114548	NLRP3	1
730249	ACOD1	4
5984	RFC4	2
695	BTK	5
1984	EIF5A	3
7088	TLE1	3
284217	LAMA1	2
7424	VEGFC	3
83931	STK40	3
4982	TNFRSF11B	5
1992	SERPINB1	5
399979	SNX19	3
375449	MAST4	3
22858	ICK	2
6850	SYK	2
8643	PTCH2	1
65217	PCDH15	6
79971	WLS	2
9020	MAP3K14	3
5534	PPP3R1	3
23191	CYFIP1	2
7525	YES1	3
29760	BLNK	3
1973	EIF4A1	5
50488	MINK1	2
2068	ERCC2	3
80312	TET1	2
4605	MYBL2	3
1009	CDH11	2
2734	GLG1	2
8038	ADAM12	3
1496	CTNNA2	2
7533	YWHAH	7
5450	POU2AF1	3
91461	PKDCC	6
23152	CIC	1
2066	ERBB4	6
904	CCNT1	3
28951	TRIB2	2
1029	CDKN2A	1
5460	POU5F1	3
959	CD40LG	3
57523	NYNRIN	2
2868	GRK4	2
861	RUNX1	1
27347	STK39	6
149420	PDIK1L	3
58508	KMT2C	2
4173	MCM4	1
2322	FLT3	2
57194	ATP10A	2
960	CD44	1
7170	TPM3	2
2329	FMO4	2
93210	PGAP3	1
4086	SMAD1	1
5585	PKN1	2
1649	DDIT3	3
11213	IRAK3	3
84075	FSCB	5
344387	CDKL4	3
1555	CYP2B6	3
2309	FOXO3	1
65125	WNK1	2
7175	TPR	3
5871	MAP4K2	3
80205	CHD9	2
2000	ELF4	2
2081	ERN1	5
4026	LPP	2
8997	KALRN	3
2071	ERCC3	2
5888	RAD51	3
57111	RAB25	1
170692	ADAMTS18	2
8288	EPX	1
6654	SOS1	2
2737	GLI3	3
51366	UBR5	2
5297	PI4KA	2
54756	IL17RD	6
501	ALDH7A1	2
10926	DBF4	1
10535	RNASEH2A	3
4958	OMD	3
4214	MAP3K1	6
440275	EIF2AK4	3
602	BCL3	3
9972	NUP153	2
3239	HOXD13	3
50615	IL21R	5
3720	JARID2	5
1514	CTSL	2
5034	P4HB	3
4293	MAP3K9	1
90	ACVR1	3
253260	RICTOR	3
85366	MYLK2	6
2318	FLNC	3
607	BCL9	1
157680	VPS13B	1
4609	MYC	1
5789	PTPRD	4
10461	MERTK	2
7297	TYK2	2
5462	POU5F1B	7
896	CCND3	3
51265	CDKL3	2
5663	PSEN1	2
5156	PDGFRA	2
1022	CDK7	9
6872	TAF1	2
84630	TTBK1	6
22976	PAXIP1	1
83452	RAB33B	2
3485	IGFBP2	1
120892	LRRK2	2
100272147	CMC4	6
79184	BRCC3	2
694	BTG1	2
7468	NSD2	2
9113	LATS1	1
460	ASTN1	2
7286	TUFT1	3
11262	SP140	4
6615	SNAI1	1
1230	CCR1	5
4791	NFKB2	3
10010	TANK	3
55521	TRIM36	2
23476	BRD4	2
5728	PTEN	1
51330	TNFRSF12A	3
1487	CTBP1	2
80124	VCPIP1	3
23281	MTUS2	3
1974	EIF4A2	5
5305	PIP4K2A	2
2897	GRIK1	2
85409	NKD2	3
10962	MLLT11	1
658	BMPR1B	2
5896	RAG1	3
2870	GRK6	7
6498	SKIL	2
28954	REM1	2
79834	PEAK1	2
3577	CXCR1	3
348378	SHISAL2A	3
7454	WAS	1
10562	OLFM4	3
203447	NRK	3
6787	NEK4	2
8667	EIF3H	3
53904	MYO3A	4
29941	PKN3	3
3161	HMMR	5
128869	PIGU	3
10243	GPHN	8
286151	FBXO43	5
51151	SLC45A2	6
558	AXL	1
7248	TSC1	3
3985	LIMK2	3
57680	CHD8	2
317	APAF1	1
2690	GHR	3
2317	FLNB	3
778	CACNA1F	2
171389	NLRP6	2
53353	LRP1B	1
7094	TLN1	2
3181	HNRNPA2B1	2
9201	DCLK1	2
4000	LMNA	3
54101	RIPK4	8
283455	KSR2	9
2194	FASN	5
598	BCL2L1	2
5587	PRKD1	2
1719	DHFR	3
57448	BIRC6	2
2131	EXT1	3
2157	F8	3
57147	SCYL3	2
4067	LYN	3
150094	SIK1	1
51562	MBIP	2
5915	RARB	1
8569	MKNK1	3
3656	IRAK2	2
84072	HORMAD1	3
23250	ATP11A	3
182	JAG1	2
80781	COL18A1	2
1760	DMPK	2
5087	PBX1	1
5054	SERPINE1	2
6653	SORL1	3
4974	OMG	5
4666	NACA	3
4217	MAP3K5	1
2065	ERBB3	1
3131	HLF	2
25	ABL1	2
1576	CYP3A4	2
7040	TGFB1	3
55959	SULF2	2
57120	GOPC	3
50964	SOST	3
5049	PAFAH1B2	3
2261	FGFR3	5
23072	HECW1	3
5567	PRKACB	5
55422	ZNF331	2
595	CCND1	3
4763	NF1	5
8814	CDKL1	3
63893	UBE2O	4
1840	DTX1	4
6886	TAL1	3
10048	RANBP9	2
7294	TXK	2
3440	IFNA2	2
1795	DOCK3	1
167359	NIM1K	2
2904	GRIN2B	2
5624	PROC	5
5970	RELA	5

Gene in drug-gene network: Network Plot

Models in Austocystin D

SITE

DATATYPES

CLASSFICATION

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