CDKL1

Summary: This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namecyclin dependent kinase like 1
OMIM IDMIM:603441
Ensembl IDEnsembl:ENSG00000100490
HGNC IDHGNC:HGNC:1781
PHARMGKB IDPA26317
Map Location14q21.3

GO terms in CDKL1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004693 cyclin-dependent protein serine/threonine kinase activity
MF IEA GO:0005524 ATP binding
BP IBA GO:0006468 protein phosphorylation
BP IEA GO:0007507 heart development
BP IEA GO:0051726 regulation of cell cycle
BP ISS GO:1902017 regulation of cilium assembly
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Gene expression in normal tissue: CDKL1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined14p53 pathway1Metabolism1Chromatin histone acetylation1Apoptosis regulation1Proteasome1Purine metabolism1Stilbenoid, diarylheptanoid and gingerol biosynthesis1

Pathways in CDKL1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD79 Gemcitabine 3
iGMDRD889 Compound 7d-cis 6
iGMDRD297 Austocystin D 3
iGMDRD61 Kinetin riboside 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CDKL1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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