CDKL1


Summary: This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
cyclin dependent kinase like 1MIM:603441Ensembl:ENSG00000100490HGNC:HGNC:1781PA2631714q21.3

GO terms in CDKL1


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0004693cyclin-dependent protein serine/threonine kinase activity
MFIEAGO:0005524ATP binding
BPIBAGO:0006468protein phosphorylation
BPIEAGO:0007507heart development
BPIEAGO:0051726regulation of cell cycle
BPISSGO:1902017regulation of cilium assembly
CCIBAGO:0005634nucleus
CCIDAGO:0005654nucleoplasm
CCIEAGO:0005737cytoplasm
CCISSGO:0035869ciliary transition zone
CCIDAGO:0043231intracellular membrane-bounded organelle
CCHDAGO:0070062extracellular exosome

Gene expression in normal tissue: CDKL1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CDKL1


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD79Gemcitabine3
iGMDRD889Compound 7d-cis6
iGMDRD297Austocystin D3
iGMDRD61Kinetin riboside3
iGMDRD152179324-69-73
iGMDRD446LY 21832401
iGMDRD85Ursolic acid3
iGMDRD318PAC-11
iGMDRD187BRD98761
iGMDRD202Curcumin2
iGMDRD121GMX17786
iGMDRD42Vorinostat3
iGMDRD451Serdemetan1
iGMDRD322FK 8663
iGMDRD886Compound 1541A3
iGMDRD369TGX-1153
iGMDRD888Compound 446
iGMDRD329Merck606
iGMDRD188Piperlongumine3
iGMDRD871BRD63683
iGMDRD872BRD71379

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CDKL1

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