iGMDRD446
Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
---|---|---|---|---|
LY 2183240 | CHEMBL509860 | 11507800 | Alone | Small Molecule |
Drug Targets:
FAAHDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene ID | Gene Name | Model Num. |
---|---|---|
331 | XIAP | 1 |
1147 | CHUK | 2 |
27102 | EIF2AK1 | 3 |
27125 | AFF4 | 2 |
4854 | NOTCH3 | 3 |
7514 | XPO1 | 1 |
8999 | CDKL2 | 3 |
6664 | SOX11 | 3 |
5296 | PIK3R2 | 3 |
81037 | CLPTM1L | 2 |
5027 | P2RX7 | 3 |
10903 | MTMR11 | 1 |
471 | ATIC | 2 |
79848 | CSPP1 | 1 |
7535 | ZAP70 | 2 |
1464 | CSPG4 | 2 |
10641 | NPRL2 | 3 |
23085 | ERC1 | 4 |
8444 | DYRK3 | 1 |
10987 | COPS5 | 4 |
9261 | MAPKAPK2 | 4 |
132 | ADK | 4 |
7421 | VDR | 3 |
26191 | PTPN22 | 1 |
7750 | ZMYM2 | 4 |
4926 | NUMA1 | 3 |
11183 | MAP4K5 | 2 |
2986 | GUCY2F | 1 |
79947 | DHDDS | 3 |
4627 | MYH9 | 4 |
5546 | PRCC | 4 |
8929 | PHOX2B | 3 |
10806 | SDCCAG8 | 3 |
2956 | MSH6 | 8 |
57679 | ALS2 | 3 |
3708 | ITPR1 | 3 |
57554 | LRRC7 | 2 |
9706 | ULK2 | 1 |
7272 | TTK | 5 |
6563 | SLC14A1 | 4 |
55215 | FANCI | 3 |
8289 | ARID1A | 3 |
80070 | ADAMTS20 | 1 |
8266 | UBL4A | 2 |
701 | BUB1B | 5 |
8573 | CASK | 1 |
5934 | RBL2 | 2 |
2335 | FN1 | 5 |
4928 | NUP98 | 5 |
9760 | TOX | 3 |
3431 | SP110 | 3 |
2475 | MTOR | 2 |
83942 | TSSK1B | 3 |
150209 | AIFM3 | 2 |
3326 | HSP90AB1 | 2 |
9869 | SETDB1 | 6 |
4036 | LRP2 | 9 |
7764 | ZNF217 | 3 |
11160 | ERLIN2 | 2 |
5133 | PDCD1 | 1 |
11116 | FGFR1OP | 5 |
10320 | IKZF1 | 1 |
79820 | CATSPERB | 6 |
7444 | VRK2 | 1 |
390502 | SERPINA2 | 3 |
64783 | RBM15 | 1 |
4771 | NF2 | 5 |
1786 | DNMT1 | 6 |
10863 | ADAM28 | 3 |
6598 | SMARCB1 | 4 |
9891 | NUAK1 | 2 |
4170 | MCL1 | 3 |
1136 | CHRNA3 | 1 |
1607 | DGKB | 1 |
1272 | CNTN1 | 4 |
3066 | HDAC2 | 3 |
10142 | AKAP9 | 3 |
7253 | TSHR | 1 |
5298 | PI4KB | 3 |
8749 | ADAM18 | 3 |
2241 | FER | 2 |
55534 | MAML3 | 3 |
8737 | RIPK1 | 1 |
1404 | HAPLN1 | 4 |
22821 | RASA3 | 4 |
1545 | CYP1B1 | 1 |
79934 | COQ8B | 3 |
54822 | TRPM7 | 4 |
577 | ADGRB3 | 2 |
114783 | LMTK3 | 1 |
1387 | CREBBP | 2 |
1893 | ECM1 | 2 |
5756 | TWF1 | 1 |
10454 | TAB1 | 3 |
3727 | JUND | 3 |
55023 | PHIP | 1 |
1859 | DYRK1A | 3 |
23225 | NUP210 | 5 |
2313 | FLI1 | 2 |
11200 | CHEK2 | 4 |
31 | ACACA | 2 |
1602 | DACH1 | 1 |
10178 | TENM1 | 3 |
51755 | CDK12 | 2 |
79858 | NEK11 | 4 |
5596 | MAPK4 | 2 |
57472 | CNOT6 | 3 |
5966 | REL | 3 |
3604 | TNFRSF9 | 4 |
29998 | BICRA | 1 |
8295 | TRRAP | 1 |
10438 | C1D | 1 |
11122 | PTPRT | 3 |
5396 | PRRX1 | 3 |
7373 | COL14A1 | 7 |
5166 | PDK4 | 2 |
55300 | PI4K2B | 2 |
7173 | TPO | 6 |
10215 | OLIG2 | 3 |
4851 | NOTCH1 | 2 |
2120 | ETV6 | 2 |
139378 | ADGRG4 | 2 |
7158 | TP53BP1 | 2 |
55294 | FBXW7 | 2 |
10295 | BCKDK | 3 |
2033 | EP300 | 6 |
8030 | CCDC6 | 4 |
9578 | CDC42BPB | 1 |
641 | BLM | 2 |
83439 | TCF7L1 | 3 |
55728 | N4BP2 | 1 |
3227 | HOXC11 | 4 |
10818 | FRS2 | 1 |
25925 | ZNF521 | 3 |
54477 | PLEKHA5 | 3 |
57670 | KIAA1549 | 2 |
22861 | NLRP1 | 3 |
440279 | UNC13C | 3 |
4610 | MYCL | 4 |
4301 | AFDN | 2 |
84033 | OBSCN | 3 |
342667 | STAC2 | 1 |
51776 | MAP3K20 | 2 |
342977 | NANOS3 | 3 |
256646 | NUTM1 | 3 |
1540 | CYLD | 3 |
8600 | TNFSF11 | 3 |
7025 | NR2F1 | 2 |
9693 | RAPGEF2 | 3 |
23012 | STK38L | 6 |
57787 | MARK4 | 4 |
1586 | CYP17A1 | 2 |
1591 | CYP24A1 | 4 |
32 | ACACB | 5 |
8852 | AKAP4 | 2 |
3556 | IL1RAP | 2 |
329 | BIRC2 | 2 |
8396 | PIP4K2B | 3 |
2688 | GH1 | 3 |
2242 | FES | 2 |
10342 | TFG | 3 |
4005 | LMO2 | 1 |
3645 | INSRR | 2 |
22984 | PDCD11 | 2 |
6041 | RNASEL | 3 |
9175 | MAP3K13 | 2 |
8313 | AXIN2 | 3 |
6733 | SRPK2 | 1 |
6091 | ROBO1 | 2 |
2042 | EPHA3 | 1 |
1050 | CEBPA | 1 |
2260 | FGFR1 | 3 |
51343 | FZR1 | 2 |
23255 | MTCL1 | 5 |
114548 | NLRP3 | 1 |
730249 | ACOD1 | 6 |
10188 | TNK2 | 1 |
10217 | CTDSPL | 2 |
11169 | WDHD1 | 3 |
4216 | MAP3K4 | 3 |
2736 | GLI2 | 2 |
6198 | RPS6KB1 | 1 |
597 | BCL2A1 | 3 |
83990 | BRIP1 | 7 |
51804 | SIX4 | 4 |
4739 | NEDD9 | 3 |
4194 | MDM4 | 4 |
284217 | LAMA1 | 2 |
269 | AMHR2 | 3 |
83931 | STK40 | 2 |
55681 | SCYL2 | 3 |
2045 | EPHA7 | 2 |
23405 | DICER1 | 1 |
238 | ALK | 2 |
1277 | COL1A1 | 5 |
7078 | TIMP3 | 3 |
171019 | ADAMTS19 | 1 |
375449 | MAST4 | 3 |
983 | CDK1 | 3 |
287015 | TRIM42 | 1 |
8643 | PTCH2 | 5 |
65217 | PCDH15 | 2 |
8395 | PIP5K1B | 2 |
26750 | RPS6KC1 | 5 |
834 | CASP1 | 3 |
79971 | WLS | 2 |
54899 | PXK | 3 |
286826 | LIN9 | 3 |
7486 | WRN | 4 |
23191 | CYFIP1 | 6 |
440730 | TRIM67 | 3 |
5573 | PRKAR1A | 2 |
23387 | SIK3 | 7 |
783 | CACNB2 | 10 |
4140 | MARK3 | 4 |
8714 | ABCC3 | 4 |
5286 | PIK3C2A | 5 |
1973 | EIF4A1 | 3 |
158056 | MAMDC4 | 5 |
6793 | STK10 | 1 |
50488 | MINK1 | 6 |
2068 | ERCC2 | 2 |
5591 | PRKDC | 2 |
6098 | ROS1 | 1 |
9472 | AKAP6 | 2 |
54437 | SEMA5B | 3 |
8515 | ITGA10 | 5 |
2778 | GNAS | 3 |
130497 | OSR1 | 1 |
6917 | TCEA1 | 4 |
80243 | PREX2 | 6 |
472 | ATM | 3 |
8945 | BTRC | 6 |
5165 | PDK3 | 4 |
1009 | CDH11 | 3 |
139285 | AMER1 | 1 |
8148 | TAF15 | 1 |
28996 | HIPK2 | 1 |
9564 | BCAR1 | 4 |
4804 | NGFR | 1 |
4058 | LTK | 2 |
6792 | CDKL5 | 1 |
1123 | CHN1 | 3 |
1496 | CTNNA2 | 1 |
7010 | TEK | 4 |
5450 | POU2AF1 | 1 |
23152 | CIC | 3 |
2272 | FHIT | 1 |
2066 | ERBB4 | 4 |
7681 | MKRN3 | 2 |
904 | CCNT1 | 3 |
1647 | GADD45A | 3 |
56648 | EIF5A2 | 3 |
51517 | NCKIPSD | 3 |
79442 | LRRC2 | 4 |
10413 | YAP1 | 6 |
1029 | CDKN2A | 2 |
7184 | HSP90B1 | 2 |
9794 | MAML1 | 3 |
5129 | CDK18 | 2 |
23048 | FNBP1 | 4 |
57523 | NYNRIN | 4 |
1910 | EDNRB | 4 |
2868 | GRK4 | 2 |
5336 | PLCG2 | 3 |
10018 | BCL2L11 | 2 |
5834 | PYGB | 1 |
55190 | NUDT11 | 2 |
3932 | LCK | 4 |
58508 | KMT2C | 4 |
648 | BMI1 | 4 |
7157 | TP53 | 1 |
7704 | ZBTB16 | 2 |
79058 | ASPSCR1 | 1 |
6714 | SRC | 6 |
6794 | STK11 | 2 |
4296 | MAP3K11 | 2 |
2322 | FLT3 | 1 |
57194 | ATP10A | 5 |
25836 | NIPBL | 3 |
7869 | SEMA3B | 2 |
8218 | CLTCL1 | 5 |
3791 | KDR | 1 |
10114 | HIPK3 | 2 |
836 | CASP3 | 2 |
6772 | STAT1 | 3 |
93210 | PGAP3 | 1 |
114788 | CSMD3 | 2 |
2263 | FGFR2 | 6 |
4086 | SMAD1 | 1 |
5585 | PKN1 | 4 |
1019 | CDK4 | 3 |
65243 | ZFP69B | 7 |
11213 | IRAK3 | 3 |
84075 | FSCB | 2 |
9967 | THRAP3 | 3 |
1045 | CDX2 | 1 |
105 | ADARB2 | 2 |
8833 | GMPS | 3 |
5604 | MAP2K1 | 3 |
64386 | MMP25 | 1 |
863 | CBFA2T3 | 2 |
51086 | TNNI3K | 3 |
1102 | RCBTB2 | 2 |
5600 | MAPK11 | 2 |
2309 | FOXO3 | 2 |
4921 | DDR2 | 3 |
3572 | IL6ST | 4 |
6197 | RPS6KA3 | 4 |
57188 | ADAMTSL3 | 2 |
3187 | HNRNPH1 | 1 |
55589 | BMP2K | 4 |
65125 | WNK1 | 2 |
136332 | LRGUK | 4 |
4436 | MSH2 | 1 |
652 | BMP4 | 3 |
6035 | RNASE1 | 2 |
984 | CDK11B | 1 |
7175 | TPR | 5 |
5871 | MAP4K2 | 7 |
54106 | TLR9 | 4 |
80205 | CHD9 | 2 |
57578 | UNC79 | 1 |
8997 | KALRN | 3 |
23269 | MGA | 1 |
7994 | KAT6A | 3 |
57111 | RAB25 | 1 |
6280 | S100A9 | 2 |
2175 | FANCA | 3 |
23469 | PHF3 | 3 |
4089 | SMAD4 | 2 |
51284 | TLR7 | 4 |
7471 | WNT1 | 2 |
6654 | SOS1 | 7 |
672 | BRCA1 | 3 |
2060 | EPS15 | 3 |
2668 | GDNF | 1 |
11168 | PSIP1 | 3 |
1848 | DUSP6 | 1 |
2737 | GLI3 | 3 |
7204 | TRIO | 4 |
9252 | RPS6KA5 | 2 |
285220 | EPHA6 | 2 |
51366 | UBR5 | 1 |
23678 | SGK3 | 6 |
5297 | PI4KA | 2 |
2047 | EPHB1 | 2 |
54756 | IL17RD | 3 |
5069 | PAPPA | 3 |
501 | ALDH7A1 | 1 |
10769 | PLK2 | 3 |
5578 | PRKCA | 3 |
4214 | MAP3K1 | 2 |
3702 | ITK | 2 |
9972 | NUP153 | 6 |
3239 | HOXD13 | 6 |
5290 | PIK3CA | 5 |
3562 | IL3 | 3 |
92335 | STRADA | 3 |
3720 | JARID2 | 2 |
1514 | CTSL | 3 |
5034 | P4HB | 3 |
1000 | CDH2 | 6 |
1687 | GSDME | 3 |
5770 | PTPN1 | 6 |
26524 | LATS2 | 6 |
5045 | FURIN | 2 |
85366 | MYLK2 | 6 |
10565 | ARFGEF1 | 4 |
64919 | BCL11B | 2 |
57154 | SMURF1 | 3 |
675 | BRCA2 | 3 |
3458 | IFNG | 1 |
26166 | RGS22 | 3 |
607 | BCL9 | 5 |
10155 | TRIM28 | 3 |
7075 | TIE1 | 1 |
1956 | EGFR | 6 |
8445 | DYRK2 | 3 |
640 | BLK | 6 |
157680 | VPS13B | 2 |
841 | CASP8 | 3 |
2735 | GLI1 | 2 |
3065 | HDAC1 | 3 |
4609 | MYC | 2 |
11064 | CNTRL | 10 |
2624 | GATA2 | 2 |
3308 | HSPA4 | 4 |
5789 | PTPRD | 4 |
5155 | PDGFB | 3 |
1459 | CSNK2A2 | 3 |
8013 | NR4A3 | 3 |
10461 | MERTK | 3 |
51321 | AMZ2 | 2 |
6885 | MAP3K7 | 3 |
26278 | SACS | 3 |
894 | CCND2 | 2 |
51265 | CDKL3 | 3 |
6446 | SGK1 | 1 |
3553 | IL1B | 6 |
1594 | CYP27B1 | 1 |
5747 | PTK2 | 3 |
5156 | PDGFRA | 1 |
7443 | VRK1 | 4 |
3635 | INPP5D | 2 |
375056 | MIA3 | 6 |
10000 | AKT3 | 4 |
91754 | NEK9 | 2 |
93627 | TBCK | 4 |
137872 | ADHFE1 | 2 |
27330 | RPS6KA6 | 2 |
10186 | LHFPL6 | 1 |
203102 | ADAM32 | 3 |
673 | BRAF | 4 |
7153 | TOP2A | 4 |
84630 | TTBK1 | 4 |
1213 | CLTC | 1 |
84879 | MFSD2A | 3 |
1769 | DNAH8 | 2 |
22976 | PAXIP1 | 3 |
3315 | HSPB1 | 1 |
23532 | PRAME | 3 |
4863 | NPAT | 3 |
780 | DDR1 | 2 |
83452 | RAB33B | 4 |
8924 | HERC2 | 4 |
120892 | LRRK2 | 1 |
65268 | WNK2 | 2 |
7027 | TFDP1 | 1 |
6095 | RORA | 5 |
57507 | ZNF608 | 2 |
84441 | MAML2 | 1 |
7468 | NSD2 | 2 |
8626 | TP63 | 2 |
9113 | LATS1 | 4 |
460 | ASTN1 | 3 |
9064 | MAP3K6 | 1 |
7849 | PAX8 | 1 |
9321 | TRIP11 | 4 |
9451 | EIF2AK3 | 4 |
654780 | LOC654780 | 1 |
11262 | SP140 | 2 |
8491 | MAP4K3 | 1 |
1230 | CCR1 | 1 |
9509 | ADAMTS2 | 1 |
5563 | PRKAA2 | 3 |
23396 | PIP5K1C | 2 |
10010 | TANK | 2 |
8312 | AXIN1 | 1 |
55521 | TRIM36 | 3 |
23476 | BRD4 | 4 |
5728 | PTEN | 1 |
51330 | TNFRSF12A | 3 |
7155 | TOP2B | 2 |
4914 | NTRK1 | 4 |
22883 | CLSTN1 | 4 |
667 | DST | 3 |
115701 | ALPK2 | 8 |
4004 | LMO1 | 3 |
284086 | NEK8 | 3 |
3554 | IL1R1 | 3 |
53836 | GPR87 | 4 |
1613 | DAPK3 | 3 |
352909 | DNAAF3 | 2 |
140803 | TRPM6 | 2 |
6770 | STAR | 1 |
2188 | FANCF | 3 |
6146 | RPL22 | 1 |
2324 | FLT4 | 2 |
5896 | RAG1 | 4 |
1676 | DFFA | 3 |
8301 | PICALM | 3 |
3899 | AFF3 | 1 |
28954 | REM1 | 2 |
7273 | TTN | 4 |
8522 | GAS7 | 3 |
79834 | PEAK1 | 4 |
7465 | WEE1 | 3 |
2119 | ETV5 | 6 |
23389 | MED13L | 2 |
10562 | OLFM4 | 1 |
29959 | NRBP1 | 2 |
8667 | EIF3H | 3 |
29941 | PKN3 | 1 |
79012 | CAMKV | 4 |
2046 | EPHA8 | 1 |
10249 | GLYAT | 1 |
1027 | CDKN1B | 2 |
128869 | PIGU | 3 |
8821 | INPP4B | 3 |
84930 | MASTL | 4 |
5532 | PPP3CB | 3 |
22843 | PPM1E | 4 |
8394 | PIP5K1A | 3 |
2353 | FOS | 4 |
286151 | FBXO43 | 4 |
57820 | CCNB1IP1 | 3 |
26686 | OR4E2 | 3 |
1662 | DDX10 | 2 |
10595 | ERN2 | 2 |
344905 | ATP13A5 | 3 |
5588 | PRKCQ | 3 |
4297 | KMT2A | 3 |
7248 | TSC1 | 4 |
9748 | SLK | 3 |
4619 | MYH1 | 2 |
57680 | CHD8 | 3 |
2869 | GRK5 | 4 |
5581 | PRKCE | 3 |
5923 | RASGRF1 | 3 |
1399 | CRKL | 2 |
2317 | FLNB | 5 |
10111 | RAD50 | 1 |
100124696 | TEC | 3 |
6790 | AURKA | 5 |
9223 | MAGI1 | 1 |
5395 | PMS2 | 2 |
171389 | NLRP6 | 1 |
1789 | DNMT3B | 2 |
53353 | LRP1B | 2 |
55289 | ACOXL | 4 |
9659 | PDE4DIP | 3 |
63976 | PRDM16 | 6 |
283455 | KSR2 | 2 |
6760 | SS18 | 1 |
131890 | GRK7 | 9 |
5927 | KDM5A | 3 |
3579 | CXCR2 | 1 |
5587 | PRKD1 | 4 |
5111 | PCNA | 1 |
55007 | FAM118A | 3 |
1719 | DHFR | 4 |
10734 | STAG3 | 3 |
5589 | PRKCSH | 5 |
2321 | FLT1 | 3 |
57448 | BIRC6 | 2 |
2131 | EXT1 | 3 |
57007 | ACKR3 | 1 |
2304 | FOXE1 | 4 |
2157 | F8 | 4 |
53335 | BCL11A | 2 |
79837 | PIP4K2C | 2 |
3709 | ITPR2 | 2 |
6778 | STAT6 | 3 |
8899 | PRPF4B | 4 |
4067 | LYN | 4 |
23301 | EHBP1 | 4 |
1030 | CDKN2B | 1 |
6777 | STAT5B | 5 |
3552 | IL1A | 2 |
5932 | RBBP8 | 3 |
3977 | LIFR | 1 |
3656 | IRAK2 | 3 |
84072 | HORMAD1 | 4 |
444 | ASPH | 3 |
23250 | ATP11A | 4 |
182 | JAG1 | 7 |
2122 | MECOM | 4 |
5087 | PBX1 | 1 |
3815 | KIT | 1 |
2903 | GRIN2A | 1 |
4974 | OMG | 3 |
5925 | RB1 | 1 |
4217 | MAP3K5 | 2 |
4893 | NRAS | 1 |
1209 | CLPTM1 | 2 |
5584 | PRKCI | 1 |
2065 | ERBB3 | 4 |
2074 | ERCC6 | 2 |
862 | RUNX1T1 | 4 |
8661 | EIF3A | 1 |
7403 | KDM6A | 1 |
54790 | TET2 | 1 |
1234 | CCR5 | 2 |
2534 | FYN | 1 |
2258 | FGF13 | 3 |
4302 | MLLT6 | 3 |
4638 | MYLK | 3 |
7040 | TGFB1 | 6 |
30849 | PIK3R4 | 1 |
55959 | SULF2 | 4 |
9878 | TOX4 | 4 |
57120 | GOPC | 3 |
3488 | IGFBP5 | 2 |
3480 | IGF1R | 2 |
2011 | MARK2 | 1 |
51135 | IRAK4 | 1 |
10494 | STK25 | 3 |
11086 | ADAM29 | 1 |
9262 | STK17B | 1 |
374 | AREG | 3 |
2261 | FGFR3 | 3 |
139604 | MAGEB16 | 2 |
55422 | ZNF331 | 3 |
1013 | CDH15 | 3 |
8321 | FZD1 | 3 |
4763 | NF1 | 1 |
8814 | CDKL1 | 1 |
1612 | DAPK1 | 2 |
5260 | PHKG1 | 6 |
138474 | TAF1L | 3 |
63893 | UBE2O | 6 |
1840 | DTX1 | 2 |
65975 | STK33 | 2 |
10891 | PPARGC1A | 1 |
440270 | GOLGA8B | 3 |
4286 | MITF | 1 |
2044 | EPHA5 | 1 |
5287 | PIK3C2B | 2 |
4593 | MUSK | 3 |
4629 | MYH11 | 3 |
814 | CAMK4 | 1 |
3679 | ITGA7 | 3 |
81788 | NUAK2 | 3 |
10048 | RANBP9 | 3 |
6943 | TCF21 | 4 |
4193 | MDM2 | 2 |
6868 | ADAM17 | 1 |
23112 | TNRC6B | 2 |
27255 | CNTN6 | 2 |
1803 | DPP4 | 1 |
1499 | CTNNB1 | 2 |
27151 | CPAMD8 | 3 |
64328 | XPO4 | 3 |
3440 | IFNA2 | 3 |
2892 | GRIA3 | 4 |
4916 | NTRK3 | 2 |
1795 | DOCK3 | 1 |
167359 | NIM1K | 1 |
4486 | MST1R | 3 |
1488 | CTBP2 | 1 |
Gene in drug-gene network: Network Plot
Models in LY 2183240