NEK9
Summary: This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein is activated in mitosis and, in turn, activates other family members during mitosis. This protein also mediates cellular processes that are essential for interphase progression. [provided by RefSeq, Jul 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:609798 Ensembl IDEnsembl:ENSG00000119638 HGNC IDHGNC:HGNC:18591 PHARMGKB IDPA38593 Map Location14q24.3 | |||||
GO terms in NEK9
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0005634 | nucleus |
| CC | IDA | GO:0005813 | centrosome |
| CC | TAS | GO:0005829 | cytosol |
| BP | IEA | GO:0006468 | protein phosphorylation |
| BP | TAS | GO:0007077 | mitotic nuclear envelope disassembly |
| BP | IEA | GO:0051301 | cell division |
Gene expression in normal tissue: NEK9
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NEK9
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1640170 | Cell Cycle |
| reactome | R-HSA-2980766 | Nuclear Envelope Breakdown |
| reactome | R-HSA-2980767 | Activation of NIMA Kinases NEK9, NEK6, NEK7 |
| reactome | R-HSA-3301854 | Nuclear Pore Complex (NPC) Disassembly |
| reactome | R-HSA-68875 | Mitotic Prophase |
| reactome | R-HSA-68886 | M Phase |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NEK9
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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