iGMDRD77

Canonical SMILES: CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl

InChI: InChI=1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/t25?,31-,35-/m0/s1

InChI Key: VHVPQPYKVGDNFY-ZPGVKDDISA-N

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Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard NameItraconazole
CHEMBLCHEMBL22587
Pubchem CID55283
KEGG Drug IDD00350
DRUGBANK IDDB01167
Drug StatusAlone
Drug targets (TTD)DAP000631
Drug TypeSmall Molecule

Drug Class:

14-alpha Demethylase InhibitorsAnti-Infective AgentsAntifungal AgentsAntiinfectives for Systemic UseAntimycotics for Systemic UseAzole AntifungalsAzolesChemically-Induced DisordersCombined Inhibitors of CYP3A4 and P-glycoproteinCombined Inhibitors of CYP3A4 and P-glycoprotein (Strong)Cytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A Inhibitors (strong)Cytochrome P-450 CYP3A4 InhibitorsCytochrome P-450 CYP3A4 Inhibitors (strong)Cytochrome P-450 CYP3A5 Inhibitors (strong)Cytochrome P-450 CYP3A7 Inhibitors (strong)Cytochrome P-450 Enzyme InhibitorsDrug-Related Side Effects and Adverse ReactionsEnzyme InhibitorsHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHormone AntagonistsHormones, Hormone Substitutes, and Hormone AntagonistsMetabolic Side Effects of Drugs and SubstancesP-glycoprotein/ABCB1 InhibitorsP-glycoprotein/ABCB1 SubstratesPiperazinesPotential QTc-Prolonging AgentsQTc Prolonging AgentsSteroid Synthesis InhibitorsTriazole DerivativesTriazoles


Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
1147 CHUK 3
8019 BRD3 3
7837 PXDN 3
79054 TRPM8 3
Showing 1 to 4 of 332 rows rows per page

Gene in drug-gene network: Network Plot

Models in Itraconazole

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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