MN1

Summary: Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameMN1 proto-oncogene, transcriptional regulator
OMIM IDMIM:156100
Ensembl IDEnsembl:ENSG00000169184
HGNC IDHGNC:HGNC:7180
PHARMGKB IDPA30893
Map Location22q12.1

GO terms in MN1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF ND GO:0003674 molecular_function
CC ND GO:0005575 cellular_component
BP IEA GO:0001957 intramembranous ossification
BP IEA GO:0006351 transcription, DNA-templated
BP IEA GO:0006355 regulation of transcription, DNA-templated
BP IEA GO:0007275 multicellular organism development
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Gene expression in normal tissue: MN1

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 59undefinedtissue: undefined cancer: ADENOCARCINOMA model num: 3LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 22BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 19BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 6

Gene-drug pathway distribution

undefined31Apoptosis regulation3PI3K/MTOR signaling1Chromatin histone acetylation1Mitosis1Other, kinases1ERK MAPK signaling1Terpenoid backbone biosynthesis1WNT signaling1

Pathways in MN1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD394 BX-795 1
iGMDRD280 CYTOCHALASIN B 3
iGMDRD679 Bistramide A 1
iGMDRD797 ISOX DUAL 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MN1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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