MN1
Summary: Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| MN1 proto-oncogene, transcriptional regulator | MIM:156100 | Ensembl:ENSG00000169184 | HGNC:HGNC:7180 | PA30893 | 22q12.1 |
GO terms in MN1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ND | GO:0003674 | molecular_function |
| CC | ND | GO:0005575 | cellular_component |
| BP | IEA | GO:0001957 | intramembranous ossification |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | IEA | GO:0007275 | multicellular organism development |
| BP | ND | GO:0008150 | biological_process |
Gene expression in normal tissue: MN1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MN1
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD394 | BX-795 | 1 |
| iGMDRD280 | CYTOCHALASIN B | 3 |
| iGMDRD679 | Bistramide A | 1 |
| iGMDRD797 | ISOX DUAL | 2 |
| iGMDRD61 | Kinetin riboside | 6 |
| iGMDRD554 | CHEMBL1434137 | 2 |
| iGMDRD76 | Simvastatin | 3 |
| iGMDRD126 | Tipifarnib | 4 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD599 | Salermide | 4 |
| iGMDRD387 | CHIR-99021 | 2 |
| iGMDRD60 | Quinoclamine | 4 |
| iGMDRD640 | CAY10618 | 2 |
| iGMDRD64 | Parbendazole | 1 |
| iGMDRD356 | PNU-74654 | 1 |
| iGMDRD399 | Selumetinib | 3 |
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD562 | Navitoclax | 5 |
| iGMDRD506 | Fedratinib | 3 |
| iGMDRD577 | BIX01294 | 2 |
| iGMDRD888 | Compound 44 | 2 |
| iGMDRD885 | Compound 110 | 1 |
| iGMDRD318 | PAC-1 | 4 |
| iGMDRD255 | SB225002 | 2 |
| iGMDRD123 | Isoevodiamine | 2 |
| iGMDRD901 | ELCPK | 1 |
| iGMDRD341 | Triacsin c | 3 |
| iGMDRD237 | ABT-751 | 4 |
| iGMDRD523 | Cyanoquinoline, 11 | 1 |
| iGMDRD330 | BRD4132 | 2 |
| iGMDRD148 | Pifithrin-mu | 3 |
| iGMDRD584 | VER 155008 | 3 |
| iGMDRD886 | Compound 1541A | 2 |
| iGMDRD300 | Tozasertib | 3 |
| iGMDRD414 | MST-312 | 2 |
| iGMDRD871 | BRD6368 | 5 |
| iGMDRD366 | PI-103 | 2 |
| iGMDRD434 | BMS-536924 | 6 |
| iGMDRD6 | AM-580 | 3 |
| iGMDRD289 | Parthenolide | 2 |
| iGMDRD77 | Itraconazole | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MN1
CLASSFICATION
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