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iGMDRD772

Canonical SMILES: COC(=O)C1=CC2=C(C=C1)N(C(=N2)NC(=O)C3=CC=CC=C3)CCCC4=CC=CC=C4

InChI: InChI=1S/C25H23N3O3/c1-31-24(30)20-14-15-22-21(17-20)26-25(27-23(29)19-12-6-3-7-13-19)28(22)16-8-11-18-9-4-2-5-10-18/h2-7,9-10,12-15,17H,8,11,16H2,1H3,(H,26,27,29)

InChI Key: UCGWYCMPZXDHNR-UHFFFAOYSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
BRD4770	72193900	Alone	Small Molecule

Drug Targets:

EHMT2

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
331	XIAP	6
1105	CHD1	2
6664	SOX11	6
8019	BRD3	1
10903	MTMR11	3
79848	CSPP1	2
10221	TRIB1	3
8444	DYRK3	2
6581	SLC22A3	3
132	ADK	9
3383	ICAM1	1
6774	STAT3	2
5546	PRCC	2
2339	FNTA	3
1520	CTSS	3
57554	LRRC7	6
9706	ULK2	3
7272	TTK	6
93	ACVR2B	3
3845	KRAS	3
8289	ARID1A	2
8573	CASK	2
3939	LDHA	2
5934	RBL2	2
2335	FN1	3
4928	NUP98	4
79092	CARD14	5
4352	MPL	5
6938	TCF12	3
6597	SMARCA4	1
150209	AIFM3	1
3551	IKBKB	2
4036	LRP2	3
5241	PGR	2
5133	PDCD1	1
3069	HDLBP	3
390502	SERPINA2	3
5754	PTK7	2
23235	SIK2	5
3320	HSP90AA1	5
5218	CDK14	3
55781	RIOK2	3
7253	TSHR	3
5298	PI4KB	3
2241	FER	2
9816	URB2	6
4092	SMAD7	3
577	ADGRB3	2
1387	CREBBP	11
5756	TWF1	2
2043	EPHA4	3
5788	PTPRC	6
5579	PRKCB	6
11200	CHEK2	6
31	ACACA	1
10178	TENM1	2
85021	REPS1	3
29998	BICRA	2
8295	TRRAP	3
10438	C1D	2
9024	BRSK2	2
5159	PDGFRB	3
2033	EP300	3
6927	HNF1A	3
641	BLM	2
10746	MAP3K2	3
23522	KAT6B	7
54477	PLEKHA5	2
440279	UNC13C	3
4610	MYCL	5
4301	AFDN	1
816	CAMK2B	2
55819	RNF130	3
7025	NR2F1	2
2051	EPHB6	2
8549	LGR5	2
6256	RXRA	2
3714	JAG2	2
329	BIRC2	6
26353	HSPB8	5
166614	DCLK2	2
4005	LMO2	1
6041	RNASEL	3
200576	PIKFYVE	2
8313	AXIN2	6
1050	CEBPA	3
116986	AGAP2	3
199699	DAND5	3
114548	NLRP3	3
10188	TNK2	2
29904	EEF2K	3
83990	BRIP1	3
7088	TLE1	2
284217	LAMA1	3
83931	STK40	3
171019	ADAMTS19	2
2064	ERBB2	1
85443	DCLK3	3
287015	TRIM42	8
65217	PCDH15	1
9020	MAP3K14	3
23387	SIK3	2
783	CACNB2	2
5127	CDK16	3
1452	CSNK1A1	2
29760	BLNK	3
57510	XPO5	2
6709	SPTAN1	3
8215	DVL1P1	5
1973	EIF4A1	3
2068	ERCC2	3
6464	SHC1	3
659	BMPR2	2
6098	ROS1	8
9472	AKAP6	1
2778	GNAS	2
3685	ITGAV	2
472	ATM	1
3418	IDH2	3
575	ADGRB1	2
53942	CNTN5	4
4087	SMAD2	2
84433	CARD11	2
9564	BCAR1	2
4058	LTK	2
54986	ULK4	1
1123	CHN1	4
1496	CTNNA2	3
5450	POU2AF1	8
91461	PKDCC	3
898	CCNE1	1
2050	EPHB4	3
2272	FHIT	4
2066	ERBB4	2
5863	RGL2	2
9319	TRIP13	3
139728	PNCK	3
9794	MAML1	3
27436	EML4	2
8576	STK16	3
11143	KAT7	2
28514	DLL1	3
58508	KMT2C	3
648	BMI1	3
2099	ESR1	2
7704	ZBTB16	2
6794	STK11	4
8218	CLTCL1	2
836	CASP3	2
130399	ACVR1C	6
5585	PKN1	5
7249	TSC2	3
65243	ZFP69B	5
9967	THRAP3	2
105	ADARB2	3
5604	MAP2K1	3
64386	MMP25	3
863	CBFA2T3	3
1555	CYP2B6	1
1102	RCBTB2	1
55437	STRADB	3
2309	FOXO3	2
2177	FANCD2	3
65125	WNK1	5
57591	MRTFA	3
50945	TBX22	7
652	BMP4	2
676	BRDT	3
1656	DDX6	2
5871	MAP4K2	3
80205	CHD9	2
8115	TCL1A	3
2081	ERN1	6
57578	UNC79	2
8997	KALRN	3
23269	MGA	2
3643	INSR	3
57551	TAOK1	2
23469	PHF3	2
8288	EPX	3
2668	GDNF	3
2737	GLI3	2
7204	TRIO	2
78989	COLEC11	2
5727	PTCH1	2
9448	MAP4K4	2
285220	EPHA6	4
546	ATRX	2
6134	RPL10	3
5069	PAPPA	3
10926	DBF4	4
10535	RNASEH2A	3
64840	PORCN	3
57144	PAK5	1
440275	EIF2AK4	2
9972	NUP153	3
4293	MAP3K9	2
90	ACVR1	2
5366	PMAIP1	3
7043	TGFB3	3
57154	SMURF1	2
3458	IFNG	3
28958	COA3	3
7075	TIE1	2
1956	EGFR	2
157680	VPS13B	2
4318	MMP9	1
841	CASP8	5
4609	MYC	3
64333	ARHGAP9	1
11064	CNTRL	2
2624	GATA2	2
5599	MAPK8	3
8021	NUP214	3
8013	NR4A3	3
90427	BMF	2
4684	NCAM1	2
283629	TSSK4	3
5462	POU5F1B	2
51265	CDKL3	2
5663	PSEN1	1
79759	ZNF668	2
3635	INPP5D	2
1653	DDX1	2
8900	CCNA1	1
7917	BAG6	2
1544	CYP1A2	6
27330	RPS6KA6	2
23005	MAPKBP1	3
1981	EIF4G1	1
1213	CLTC	3
84879	MFSD2A	5
1769	DNAH8	3
22976	PAXIP1	2
23532	PRAME	2
4863	NPAT	3
780	DDR1	5
83452	RAB33B	2
57538	ALPK3	3
8924	HERC2	2
6469	SHH	3
339345	NANOS2	4
120892	LRRK2	2
65268	WNK2	6
7027	TFDP1	3
6095	RORA	2
146057	TTBK2	3
93273	LEMD1	3
8178	ELL	3
5294	PIK3CG	3
1024	CDK8	2
5979	RET	6
10253	SPRY2	3
9451	EIF2AK3	2
8491	MAP4K3	3
55290	BRF2	3
9509	ADAMTS2	3
266747	RGL4	2
8621	CDK13	2
5563	PRKAA2	2
10010	TANK	6
8312	AXIN1	2
10752	CHL1	3
7030	TFE3	2
2316	FLNA	3
7155	TOP2B	3
80124	VCPIP1	2
667	DST	2
3554	IL1R1	5
83666	PARP9	3
5305	PIP4K2A	2
23542	MAPK8IP2	5
352909	DNAAF3	5
4317	MMP8	3
1950	EGF	2
5896	RAG1	3
2870	GRK6	4
23090	ZNF423	2
79834	PEAK1	2
6789	STK4	3
7036	TFR2	6
55356	SLC22A15	3
55359	STYK1	3
2277	VEGFD	2
23411	SIRT1	3
9372	ZFYVE9	6
10249	GLYAT	2
128869	PIGU	2
1643	DDB2	2
54738	FEV	3
2072	ERCC4	2
5588	PRKCQ	2
51151	SLC45A2	6
5291	PIK3CB	4
7248	TSC1	2
332	BIRC5	2
57680	CHD8	2
2041	EPHA1	2
2317	FLNB	2
5395	PMS2	3
1789	DNMT3B	2
140913	PPIAP10	3
53353	LRP1B	2
1281	COL3A1	2
2049	EPHB3	3
283455	KSR2	4
5335	PLCG1	2
131890	GRK7	3
55007	FAM118A	5
10734	STAG3	3
5589	PRKCSH	2
57448	BIRC6	2
57007	ACKR3	6
8317	CDC7	2
3717	JAK2	2
22982	DIP2C	2
2157	F8	2
79837	PIP4K2C	2
57147	SCYL3	2
6778	STAT6	3
8899	PRPF4B	2
8550	MAPKAPK5	3
3984	LIMK1	2
80216	ALPK1	3
4261	CIITA	3
4330	MN1	3
444	ASPH	3
11076	TPPP	1
7913	DEK	2
8536	CAMK1	3
2122	MECOM	4
51167	CYB5R4	6
1760	DMPK	2
9894	TELO2	3
63923	TNN	3
3691	ITGB4	2
7403	KDM6A	2
2308	FOXO1	3
2258	FGF13	3
8841	HDAC3	2
4638	MYLK	2
3716	JAK1	2
3480	IGF1R	3
2011	MARK2	2
23092	ARHGAP26	2
10494	STK25	3
139604	MAGEB16	2
84197	POMK	2
8711	TNK1	3
4040	LRP6	2
4841	NONO	3
9625	AATK	1
10891	PPARGC1A	3
57096	RPGRIP1	3
4629	MYH11	3
23112	TNRC6B	2
27255	CNTN6	2
2444	FRK	1
56155	TEX14	4
11035	RIPK3	3
5685	PSMA4	3

Gene in drug-gene network: Network Plot

Models in BRD4770

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.