NANOS2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| nanos C2HC-type zinc finger 2 | MIM:608228 | Ensembl:ENSG00000188425 | HGNC:HGNC:23292 | PA134909776 | 19q13.32 |
Gene Categories:
TUMOR SUPPRESSORGO terms in NANOS2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0003729 | mRNA binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0008270 | zinc ion binding |
| CC | ISS | GO:0000932 | P-body |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0048471 | perinuclear region of cytoplasm |
| BP | ISS | GO:0006402 | mRNA catabolic process |
| BP | IEA | GO:0007275 | multicellular organism development |
| BP | ISS | GO:0007283 | spermatogenesis |
| BP | IDA | GO:0017148 | negative regulation of translation |
| BP | IEA | GO:0030154 | cell differentiation |
| BP | ISS | GO:0030718 | germ-line stem cell population maintenance |
| BP | ISS | GO:0045835 | negative regulation of meiotic nuclear division |
| BP | IDA | GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
Gene expression in normal tissue: NANOS2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NANOS2
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD772 | BRD4770 | 4 |
| iGMDRD433 | Lexibulin | 1 |
| iGMDRD151 | CHM-1 | 2 |
| iGMDRD76 | Simvastatin | 2 |
| iGMDRD126 | Tipifarnib | 4 |
| iGMDRD193 | Fqi1 | 2 |
| iGMDRD280 | CYTOCHALASIN B | 1 |
| iGMDRD260 | FQI-2 | 2 |
| iGMDRD480 | KU0060648 | 4 |
| iGMDRD52 | Rotenone | 3 |
| iGMDRD318 | PAC-1 | 3 |
| iGMDRD398 | Sepantronium | 2 |
| iGMDRD506 | Fedratinib | 2 |
| iGMDRD887 | Compound 23 citrate | 4 |
| iGMDRD874 | BRD8958 | 1 |
| iGMDRD369 | TGX-115 | 2 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD64 | Parbendazole | 2 |
| iGMDRD512 | nutlin 3 | 2 |
| iGMDRD307 | Manumycin A | 3 |
| iGMDRD84 | Lovastatin acid | 3 |
| iGMDRD560 | MK-2206 | 2 |
| iGMDRD237 | ABT-751 | 2 |
| iGMDRD211 | (1S,3R)-RSL3 | 1 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD137 | Indisulam | 1 |
| iGMDRD77 | Itraconazole | 1 |
| iGMDRD105 | Triptolide | 2 |
| iGMDRD705 | Nakiterpiosin | 2 |
| iGMDRD366 | PI-103 | 2 |
| iGMDRD882 | CIL41 | 2 |
| iGMDRD286 | Nsc 632839 | 3 |
| iGMDRD414 | MST-312 | 6 |
| iGMDRD322 | FK 866 | 3 |
| iGMDRD505 | Pevonedistat | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NANOS2
CLASSFICATION
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