iGMDRD105


Canonical SMILES: CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C

InChI: InChI=1S/C20H24O6/c1-8(2)18-13(25-18)14-20(26-14)17(3)5-4-9-10(7-23-15(9)21)11(17)6-12-19(20,24-12)16(18)22/h8,11-14,16,22H,4-7H2,1-3H3/t11-,12-,13-,14-,16+,17-,18-,19+,20+/m0/s1

InChI Key: DFBIRQPKNDILPW-CIVMWXNOSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
TriptolideCHEMBL463763 107985DB12025AloneSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
331XIAP3
1147CHUK3
1105CHD14
27125AFF42
4854NOTCH35
7514XPO11
8999CDKL23
5296PIK3R22
79848CSPP11
7837PXDN5
79054TRPM83
1464CSPG41
10641NPRL21
23085ERC13
6491STIL1
21ABCA32
6581SLC22A32
7750ZMYM26
2048EPHB23
2956MSH62
2200FBN13
57679ALS22
57554LRRC71
347365ITIH62
8573CASK1
53616ADAM221
9263STK17A3
5916RARG2
3069HDLBP2
11116FGFR1OP3
10320IKZF12
3209HOXA132
83481EPPK11
390502SERPINA22
5754PTK71
6598SMARCB14
9891NUAK15
3694ITGB62
3066HDAC23
55781RIOK23
8749ADAM182
55534MAML33
341676NEK52
1545CYP1B13
140469MYO3B1
943TNFRSF83
577ADGRB31
4283CXCL93
10178TENM11
9070ASH2L3
5533PPP3CC3
9411ARHGAP292
8558CDK103
3604TNFRSF93
8295TRRAP2
2977GUCY1A25
10438C1D5
7373COL14A15
7158TP53BP11
145264SERPINA123
10295BCKDK4
2033EP3003
6927HNF1A2
54567DLL41
8784TNFRSF183
4001LMNB16
9578CDC42BPB3
55728N4BP22
3227HOXC113
1453CSNK1D3
6390SDHB3
440279UNC13C1
2115ETV11
5743PTGS23
10272FSTL33
342977NANOS31
256646NUTM11
23012STK38L3
57787MARK46
6418SET3
4478MSN2
3927LASP16
1586CYP17A12
8396PIP4K2B6
2242FES2
3091HIF1A3
80351TNKS22
6091ROBO13
2260FGFR16
5330PLCB24
10188TNK22
2736GLI22
6198RPS6KB12
83990BRIP18
3303HSPA1A3
6928HNF1B1
27324TOX36
207AKT12
5898RALA3
4982TNFRSF11B3
23405DICER12
1277COL1A13
94103ORMDL32
8395PIP5K1B4
993CDC25A2
54899PXK3
23191CYFIP16
4294MAP3K101
9131AIFM13
57510XPO52
1973EIF4A13
1909EDNRA2
7166TPH14
9472AKAP62
3685ITGAV3
80243PREX21
139285AMER12
83903HASPIN4
575ADGRB13
6792CDKL52
1123CHN11
1496CTNNA22
7010TEK2
5450POU2AF15
898CCNE15
2050EPHB41
2272FHIT1
10413YAP13
2201FBN21
9361LONP13
57523NYNRIN2
83694RPS6KL13
2868GRK41
5336PLCG22
10018BCL2L111
28514DLL13
27347STK392
58508KMT2C4
7157TP531
27086FOXP15
4602MYB2
79058ASPSCR12
6794STK116
7869SEMA3B1
4292MLH12
2263FGFR22
9639ARHGEF105
7249TSC24
8874ARHGEF76
1555CYP2B68
1102RCBTB23
23043TNIK2
5164PDK23
5600MAPK112
8893EIF2B53
4921DDR25
8660IRS23
5077PAX32
65125WNK13
136332LRGUK2
50945TBX225
30012TLX33
5871MAP4K24
80205CHD95
23365ARHGEF123
84181CHD62
57578UNC793
8997KALRN2
23269MGA2
7994KAT6A2
3643INSR2
54658UGT1A11
10733PLK41
835CASP22
5727PTCH11
51366UBR52
3426CFI5
3417IDH13
5297PI4KA2
3702ITK2
3239HOXD135
5290PIK3CA7
3720JARID24
5034P4HB4
1000CDH23
2318FLNC2
10565ARFGEF11
64919BCL11B1
675BRCA21
607BCL92
8445DYRK25
640BLK5
64333ARHGAP93
91ACVR1B5
5789PTPRD1
10461MERTK6
5753PTK66
7297TYK25
4684NCAM12
6885MAP3K73
894CCND21
5462POU5F1B1
29951PDZRN41
51265CDKL33
51701NLK2
5156PDGFRA1
93627TBCK4
137872ADHFE13
6872TAF11
4790NFKB13
84879MFSD2A1
1769DNAH82
988CDC5L2
3315HSPB15
23532PRAME1
4863NPAT5
5598MAPK72
339345NANOS22
120892LRRK23
65268WNK26
57507ZNF6082
7468NSD21
8029CUBN2
23118TAB23
8626TP632
9113LATS12
460ASTN12
8178ELL2
7849PAX85
9451EIF2AK32
1977EIF4E3
51555PEX5L1
8491MAP4K32
3654IRAK13
23049SMG12
8312AXIN12
5728PTEN1
57521RPTOR1
140609NEK73
1869E2F12
115701ALPK25
4004LMO13
284086NEK82
1613DAPK33
2188FANCF3
658BMPR1B3
1676DFFA3
8301PICALM2
3899AFF32
4055LTBR2
91807MYLK32
7059THBS32
8648NCOA13
79012CAMKV1
9372ZFYVE93
54861SNRK3
2046EPHA85
7150TOP12
8821INPP4B2
84930MASTL1
3207HOXA113
23305ACSL63
10595ERN22
2317FLNB3
8031NCOA42
100124696TEC2
7094TLN12
1281COL3A11
9659PDE4DIP5
2185PTK2B5
4628MYH103
5170PDPK15
7227TRPS15
6778STAT65
3516RBPJ2
6777STAT5B2
3552IL1A2
5932RBBP82
330BIRC33
1455CSNK1G22
23512SUZ126
11076TPPP2
7046TGFBR15
7913DEK6
2122MECOM3
3662IRF42
51167CYB5R45
5087PBX12
2903GRIN2A4
4217MAP3K52
7113TMPRSS24
7069THRSP1
7403KDM6A3
4638MYLK5
5586PKN22
4205MEF2A3
7040TGFB13
30849PIK3R42
3488IGFBP55
79728PALB22
4915NTRK22
4299AFF12
84446BRSK11
156GRK26
57697FANCM2
9625AATK5
63893UBE2O2
5288PIK3C2G2
2044EPHA53
3679ITGA73
81788NUAK25
3265HRAS3
2178FANCE4
1499CTNNB14
5602MAPK1010
2892GRIA33
5624PROC3

Gene in drug-gene network: Network Plot

Models in Triptolide

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