RALA
Summary: The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:179550 Ensembl IDEnsembl:ENSG00000006451 HGNC IDHGNC:HGNC:9839 PHARMGKB IDPA34197 Map Location7p14.1 | |||||
Gene Categories:
CELL SURFACEGO terms in RALA
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0003924 | GTPase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0005525 | GTP binding |
| MF | IPI | GO:0017022 | myosin binding |
| MF | IDA | GO:0019003 | GDP binding |
| MF | IPI | GO:0031625 | ubiquitin protein ligase binding |
Gene expression in normal tissue: RALA
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RALA
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04014 | Ras signaling pathway - Homo sapiens (human) |
| kegg | hsa04015 | Rap1 signaling pathway - Homo sapiens (human) |
| kegg | hsa04072 | Phospholipase D signaling pathway - Homo sapiens (human) |
| kegg | hsa05200 | Pathways in cancer - Homo sapiens (human) |
| kegg | hsa05210 | Colorectal cancer - Homo sapiens (human) |
| kegg | hsa05212 | Pancreatic cancer - Homo sapiens (human) |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RALA
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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