iGMDRD322


Canonical SMILES: C1CN(CCC1CCCCNC(=O)C=CC2=CN=CC=C2)C(=O)C3=CC=CC=C3

InChI: InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+

InChI Key: KPBNHDGDUADAGP-VAWYXSNFSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
FK 866CHEMBL566757 6914660DB12731AloneSmall Molecule


Drug Targets:

NAMPT (P43490)

Drug Pathways:

Metabolism

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
331XIAP3
3696ITGB81
64901RANBP173
10903MTMR112
79054TRPM82
1464CSPG42
8444DYRK33
10987COPS53
132ADK2
114801TMEM200A3
4168MCF23
4303FOXO42
57679ALS23
3708ITPR11
1588CYP19A12
57554LRRC73
817CAMK2D3
7272TTK4
2100ESR23
8289ARID1A3
701BUB1B1
5934RBL23
3431SP1103
6938TCF124
7850IL1R23
3326HSP90AB11
11160ERLIN22
5241PGR1
5133PDCD13
7444VRK25
7942TFEB1
390502SERPINA22
53944CSNK1G13
56776FMN21
5079PAX52
64783RBM152
10892MALT12
23235SIK24
1272CNTN11
3320HSP90AA13
3066HDAC25
22821RASA33
7080NKX2-110
577ADGRB32
5756TWF12
5788PTPRC2
23225NUP2101
2313FLI16
5579PRKCB2
11200CHEK21
1602DACH13
10178TENM12
9411ARHGAP292
3604TNFRSF92
10438C1D2
4851NOTCH11
5314PKHD13
641BLM3
1021CDK62
4595MUTYH3
55728N4BP22
25925ZNF5213
54477PLEKHA54
55819RNF1303
5607MAP2K52
256646NUTM15
122011CSNK1A1L2
2051EPHB64
9693RAPGEF25
288ANK31
32ACACB3
3556IL1RAP2
22806IKZF32
7416VDAC13
22984PDCD113
6733SRPK23
2042EPHA32
4792NFKBIA10
11169WDHD13
29904EEF2K3
83990BRIP12
3688ITGB13
284217LAMA12
1143CHRNB42
5898RALA3
55681SCYL25
2045EPHA71
23405DICER13
171019ADAMTS193
375449MAST43
2064ERBB21
85443DCLK35
55361PI4K2A3
7486WRN6
1452CSNK1A11
8714ABCC33
2068ERCC22
5568PRKACG2
659BMPR25
6098ROS11
9472AKAP67
8945BTRC2
2580GAK6
1009CDH111
139285AMER13
575ADGRB11
3397ID13
5924RASGRF23
2734GLG13
6792CDKL53
7010TEK6
23152CIC3
2050EPHB43
2066ERBB44
10290SPEG3
10062NR1H32
57523NYNRIN2
58508KMT2C2
7157TP534
6092ROBO24
6794STK114
7869SEMA3B5
8218CLTCL12
114788CSMD35
8874ARHGEF73
1555CYP2B62
51086TNNI3K3
7175TPR3
80205CHD93
23365ARHGEF121
57578UNC795
10499NCOA23
23269MGA1
51284TLR71
170692ADAMTS181
6654SOS110
2668GDNF1
78989COLEC113
5727PTCH12
51366UBR53
3417IDH11
5069PAPPA3
57144PAK52
340533NEXMIF2
8216LZTR12
3702ITK2
8731RNMT1
9972NUP1532
5290PIK3CA2
3720JARID21
1514CTSL2
1000CDH22
26524LATS22
2318FLNC3
10565ARFGEF12
57154SMURF13
7075TIE11
1956EGFR6
8445DYRK21
157680VPS13B2
4318MMP93
841CASP82
3065HDAC13
64333ARHGAP93
5789PTPRD1
10461MERTK4
100130933SMIM63
26278SACS2
51265CDKL32
6446SGK13
5156PDGFRA3
5187PER13
375056MIA32
9159PCSK72
27330RPS6KA63
84630TTBK12
1981EIF4G15
84879MFSD2A3
1769DNAH81
22976PAXIP12
4863NPAT3
83452RAB33B3
5598MAPK72
8924HERC26
339345NANOS23
120892LRRK24
11126CD1602
57507ZNF6083
5128CDK171
8626TP635
9113LATS13
8178ELL3
9451EIF2AK32
9843HEPH1
5563PRKAA22
8312AXIN15
23542MAPK8IP22
2324FLT43
1950EGF2
2264FGFR42
177AGER3
8301PICALM6
1018CDK33
79834PEAK12
203447NRK3
29959NRBP12
8648NCOA15
387RHOA4
9372ZFYVE94
54861SNRK2
84930MASTL2
8805TRIM245
2072ERCC42
10076PTPRU1
558AXL3
332BIRC52
83417FCRL43
57680CHD82
5581PRKCE2
5923RASGRF11
2317FLNB1
53353LRP1B3
5609MAP2K73
5587PRKD15
10734STAG33
5589PRKCSH1
5170PDPK11
7099TLR43
2157F82
5506PPP1R3A2
6778STAT65
57118CAMK1D3
51562MBIP9
6777STAT5B2
3552IL1A2
330BIRC33
7112TMPO3
84072HORMAD11
170685NUDT103
1760DMPK2
3815KIT3
4974OMG2
5925RB18
63923TNN3
3691ITGB42
4615MYD883
255239ANKK12
5586PKN26
10494STK256
142PARP16
2261FGFR32
2073ERCC53
4763NF11
8814CDKL13
440270GOLGA8B3
94ACVRL11
2044EPHA56
4629MYH113
10048RANBP93
7294TXK2
6868ADAM171
23112TNRC6B5
27255CNTN64
57699CPNE51
2444FRK1
56155TEX144
5624PROC1
5590PRKCZ4

Gene in drug-gene network: Network Plot

Models in FK 866

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