CDK17
Summary: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| cyclin dependent kinase 17 | MIM:603440 | Ensembl:ENSG00000059758 | HGNC:HGNC:8750 | PA33096 | 12q23.1 |
GO terms in CDK17
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | TAS | GO:0004672 | protein kinase activity |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IBA | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| BP | IBA | GO:0006468 | protein phosphorylation |
| BP | IEA | GO:0006468 | protein phosphorylation |
| CC | IBA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
Gene expression in normal tissue: CDK17
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CDK17
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD177 | Teniposide | 1 |
| iGMDRD154 | NSC23766 | 3 |
| iGMDRD375 | GW-405833 | 5 |
| iGMDRD152 | 179324-69-7 | 3 |
| iGMDRD314 | Tanespimycin | 2 |
| iGMDRD330 | BRD4132 | 3 |
| iGMDRD554 | CHEMBL1434137 | 1 |
| iGMDRD886 | Compound 1541A | 1 |
| iGMDRD322 | FK 866 | 1 |
| iGMDRD42 | Vorinostat | 2 |
| iGMDRD74 | Idarubicin | 2 |
| iGMDRD872 | BRD7137 | 3 |
| iGMDRD100 | Zebularine | 3 |
| iGMDRD286 | Nsc 632839 | 7 |
| iGMDRD171 | Pemetrexed | 1 |
| iGMDRD294 | Batimastat | 2 |
| iGMDRD187 | BRD9876 | 1 |
| iGMDRD441 | TW 37 | 1 |
| iGMDRD251 | ML162 | 6 |
| iGMDRD202 | Curcumin | 3 |
| iGMDRD158 | NSC141540 | 3 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD137 | Indisulam | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CDK17
CLASSFICATION
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