CDK17

Summary: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namecyclin dependent kinase 17
OMIM IDMIM:603440
Ensembl IDEnsembl:ENSG00000059758
HGNC IDHGNC:HGNC:8750
PHARMGKB IDPA33096
Map Location12q23.1

GO terms in CDK17


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Term Type
Evidence Type
GO Term ID
GO Des.
MF TAS GO:0004672 protein kinase activity
MF IBA GO:0004674 protein serine/threonine kinase activity
MF IBA GO:0004693 cyclin-dependent protein serine/threonine kinase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
BP IBA GO:0006468 protein phosphorylation
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Gene expression in normal tissue: CDK17

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 33BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 3BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 16OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 8

Gene-drug pathway distribution

undefined14Apoptosis regulation1Stilbenoid, diarylheptanoid and gingerol biosynthesis1DNA replication1Leukocyte transendothelial migration1Chromatin histone acetylation1Proteasome1Protein stability and degradation1Metabolism1One carbon pool by folate1

Pathways in CDK17


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD177 Teniposide 1
iGMDRD154 NSC23766 3
iGMDRD375 GW-405833 5
iGMDRD152 179324-69-7 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CDK17

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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