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iGMDRD375

Canonical SMILES: CC1=C(C2=C(N1C(=O)C3=C(C(=CC=C3)Cl)Cl)C=CC(=C2)OC)CCN4CCOCC4

InChI: InChI=1S/C23H24Cl2N2O3/c1-15-17(8-9-26-10-12-30-13-11-26)19-14-16(29-2)6-7-21(19)27(15)23(28)18-4-3-5-20(24)22(18)25/h3-7,14H,8-13H2,1-2H3

InChI Key: FSFZRNZSZYDVLI-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
GW-405833	CHEMBL73711	9911460	Alone	Small Molecule

Drug Targets:

CNR2

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
64901	RANBP17	3
9833	MELK	2
6664	SOX11	3
7074	TIAM1	2
8019	BRD3	2
81037	CLPTM1L	3
10641	NPRL2	2
132	ADK	4
7272	TTK	2
347365	ITIH6	2
3845	KRAS	2
4750	NEK1	3
2100	ESR2	3
8289	ARID1A	2
6351	CCL4	5
3939	LDHA	2
57143	ADCK1	3
25778	DSTYK	3
7764	ZNF217	2
353345	GPR141	2
9530	BAG4	2
5079	PAX5	3
51684	SUFU	3
6598	SMARCB1	5
7253	TSHR	6
3195	TLX1	3
27	ABL2	3
2241	FER	2
6318	SERPINB4	3
9816	URB2	3
6887	TAL2	3
114783	LMTK3	2
202374	STK32A	2
1387	CREBBP	2
10013	HDAC6	3
5579	PRKCB	3
5074	PAWR	3
1111	CHEK1	2
11122	PTPRT	1
23617	TSSK2	2
6722	SRF	3
55351	STK32B	3
5166	PDK4	2
5314	PKHD1	2
51512	GTSE1	3
8784	TNFRSF18	4
4361	MRE11	2
83439	TCF7L1	2
23522	KAT6B	3
342667	STAC2	6
222484	LNX2	5
6256	RXRA	2
22806	IKZF3	3
1050	CEBPA	4
23255	MTCL1	2
10188	TNK2	1
51804	SIX4	2
4982	TNFRSF11B	2
1992	SERPINB1	3
7016	TESK1	5
7078	TIMP3	3
375449	MAST4	3
22858	ICK	2
2064	ERBB2	1
85443	DCLK3	2
287015	TRIM42	5
83983	TSSK6	3
6663	SOX10	3
92	ACVR2A	2
1452	CSNK1A1	3
64170	CARD9	3
158056	MAMDC4	5
10087	COL4A3BP	6
5591	PRKDC	2
7507	XPA	3
659	BMPR2	2
130497	OSR1	3
5924	RASGRF2	2
4058	LTK	5
1496	CTNNA2	3
5289	PIK3C3	2
23152	CIC	3
2272	FHIT	4
7867	MAPKAPK3	3
9319	TRIP13	3
7184	HSP90B1	2
157753	TMEM74	3
83694	RPS6KL1	3
27347	STK39	2
7157	TP53	2
4855	NOTCH4	1
1019	CDK4	3
65243	ZFP69B	2
4869	NPM1	2
863	CBFA2T3	2
55034	MOCOS	3
652	BMP4	3
2081	ERN1	3
57578	UNC79	4
4026	LPP	1
8997	KALRN	2
4437	MSH3	4
23469	PHF3	3
672	BRCA1	3
9252	RPS6KA5	2
78989	COLEC11	2
23373	CRTC1	3
285220	EPHA6	2
5606	MAP2K3	9
10769	PLK2	3
1198	CLK3	2
2187	FANCB	3
6046	BRD2	2
2931	GSK3A	4
1956	EGFR	13
90956	ADCK2	3
8682	PEA15	1
29951	PDZRN4	3
6776	STAT5A	2
5592	PRKG1	3
1544	CYP1A2	3
3949	LDLR	2
6011	GRK1	2
120892	LRRK2	6
5128	CDK17	5
8626	TP63	5
5294	PIK3CG	3
4298	MLLT1	2
664	BNIP3	2
23598	PATZ1	3
57521	RPTOR	2
7030	TFE3	3
5595	MAPK3	2
2264	FGFR4	2
1676	DFFA	3
7042	TGFB2	3
6498	SKIL	2
7036	TFR2	3
2277	VEGFD	2
79012	CAMKV	4
22843	PPM1E	1
8394	PIP5K1A	2
2353	FOS	2
10595	ERN2	3
558	AXL	1
4619	MYH1	2
2690	GHR	6
10111	RAD50	2
7094	TLN1	2
3181	HNRNPA2B1	3
5609	MAP2K7	2
63976	PRDM16	3
7293	TNFRSF4	9
6093	ROCK1	3
3557	IL1RN	3
1719	DHFR	4
5170	PDPK1	1
8317	CDC7	2
3709	ITPR2	2
4772	NFATC1	3
51562	MBIP	3
80216	ALPK1	2
5915	RARB	3
4261	CIITA	3
84072	HORMAD1	2
2903	GRIN2A	2
5925	RB1	5
5324	PLAG1	3
3691	ITGB4	2
7508	XPC	2
112268437	LOC112268437	3
5586	PKN2	6
3488	IGFBP5	2
2073	ERCC5	2
79966	SCD5	3
4763	NF1	5
1840	DTX1	6
4629	MYH11	3
23683	PRKD3	3
1608	DGKG	2
7294	TXK	2
2444	FRK	3
2892	GRIA3	1
2886	GRB7	6
26206	SPAG8	2

Gene in drug-gene network: Network Plot

Models in GW-405833

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.