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DSTYK

Summary: This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].

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Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
Namedual serine/threonine and tyrosine protein kinase OMIM IDMIM:612666 Ensembl IDEnsembl:ENSG00000133059 HGNC IDHGNC:HGNC:29043 PHARMGKB IDPA164718861 Map Location1q32.1

Gene Categories:

DRUGGABLE GENOME TYROSINE KINASE KINASE SERINE THREONINE KINASE

GO terms in DSTYK

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Term Type	Evidence Type	GO Term ID	GO Des.
CC	IDA	GO:0005737	cytoplasm
CC	IDA	GO:0016323	basolateral plasma membrane
CC	IDA	GO:0016324	apical plasma membrane
CC	IEA	GO:0030054	cell junction
BP	IEA	GO:0018108	peptidyl-tyrosine phosphorylation
BP	IMP	GO:0033674	positive regulation of kinase activity

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Gene expression in normal tissue: DSTYK

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in DSTYK

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Database	Pathway ID	Pathway Des.
No matching records found

Gene-Drug: Aster Plot

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Drug ID	Drug Name	Model Num.
iGMDRD505	Pevonedistat	2
iGMDRD263	AACOCF3	6
iGMDRD246	NPC26	3
iGMDRD82	Quiflapon	4

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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in DSTYK

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	Model	Level	Reference ID	Tissue	Cancer	Drug	Clinical Response	Source
No matching records found

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