iGMDRD394
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| BX-795 | CHEMBL577784 | 10077100 | Alone | Small Molecule |
Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 1147 | CHUK | 2 |
| 27102 | EIF2AK1 | 2 |
| 9833 | MELK | 1 |
| 7514 | XPO1 | 1 |
| 7074 | TIAM1 | 1 |
| 3725 | JUN | 2 |
| 79054 | TRPM8 | 2 |
| 23085 | ERC1 | 2 |
| 10987 | COPS5 | 3 |
| 21 | ABCA3 | 5 |
| 6774 | STAT3 | 1 |
| 4926 | NUMA1 | 2 |
| 2986 | GUCY2F | 2 |
| 2048 | EPHB2 | 3 |
| 4627 | MYH9 | 4 |
| 5546 | PRCC | 1 |
| 2200 | FBN1 | 2 |
| 4303 | FOXO4 | 2 |
| 3708 | ITPR1 | 6 |
| 57554 | LRRC7 | 3 |
| 7272 | TTK | 6 |
| 3845 | KRAS | 2 |
| 3757 | KCNH2 | 2 |
| 5295 | PIK3R1 | 4 |
| 23097 | CDK19 | 6 |
| 8289 | ARID1A | 2 |
| 80070 | ADAMTS20 | 5 |
| 8573 | CASK | 3 |
| 51129 | ANGPTL4 | 1 |
| 25778 | DSTYK | 3 |
| 84700 | MYO18B | 3 |
| 4928 | NUP98 | 4 |
| 9475 | ROCK2 | 3 |
| 6597 | SMARCA4 | 2 |
| 3551 | IKBKB | 2 |
| 7764 | ZNF217 | 3 |
| 10395 | DLC1 | 3 |
| 11116 | FGFR1OP | 4 |
| 79820 | CATSPERB | 2 |
| 7444 | VRK2 | 2 |
| 29888 | STRN4 | 1 |
| 7942 | TFEB | 1 |
| 6657 | SOX2 | 3 |
| 5754 | PTK7 | 1 |
| 56776 | FMN2 | 4 |
| 5079 | PAX5 | 3 |
| 57580 | PREX1 | 1 |
| 4771 | NF2 | 3 |
| 1136 | CHRNA3 | 3 |
| 3320 | HSP90AA1 | 3 |
| 10142 | AKAP9 | 1 |
| 22853 | LMTK2 | 3 |
| 7253 | TSHR | 1 |
| 23310 | NCAPD3 | 2 |
| 6732 | SRPK1 | 3 |
| 27 | ABL2 | 3 |
| 2623 | GATA1 | 1 |
| 1545 | CYP1B1 | 3 |
| 7048 | TGFBR2 | 3 |
| 51199 | NIN | 1 |
| 1813 | DRD2 | 3 |
| 26039 | SS18L1 | 2 |
| 127933 | UHMK1 | 3 |
| 1859 | DYRK1A | 4 |
| 5788 | PTPRC | 1 |
| 2313 | FLI1 | 2 |
| 7133 | TNFRSF1B | 2 |
| 5175 | PECAM1 | 1 |
| 29998 | BICRA | 2 |
| 26576 | SRPK3 | 3 |
| 23617 | TSSK2 | 1 |
| 9024 | BRSK2 | 3 |
| 7373 | COL14A1 | 2 |
| 7173 | TPO | 3 |
| 10215 | OLIG2 | 1 |
| 51512 | GTSE1 | 1 |
| 7158 | TP53BP1 | 2 |
| 145264 | SERPINA12 | 1 |
| 4001 | LMNB1 | 2 |
| 64324 | NSD1 | 1 |
| 7307 | U2AF1 | 1 |
| 83439 | TCF7L1 | 1 |
| 23522 | KAT6B | 3 |
| 7852 | CXCR4 | 3 |
| 4301 | AFDN | 1 |
| 816 | CAMK2B | 1 |
| 11073 | TOPBP1 | 2 |
| 122011 | CSNK1A1L | 3 |
| 2051 | EPHB6 | 2 |
| 4478 | MSN | 3 |
| 32 | ACACB | 4 |
| 8396 | PIP4K2B | 1 |
| 22806 | IKZF3 | 4 |
| 5468 | PPARG | 1 |
| 2042 | EPHA3 | 2 |
| 114548 | NLRP3 | 5 |
| 5984 | RFC4 | 6 |
| 10188 | TNK2 | 1 |
| 2736 | GLI2 | 6 |
| 83990 | BRIP1 | 1 |
| 4739 | NEDD9 | 3 |
| 399979 | SNX19 | 1 |
| 375449 | MAST4 | 1 |
| 2064 | ERBB2 | 3 |
| 65266 | WNK4 | 4 |
| 287015 | TRIM42 | 2 |
| 57476 | GRAMD1B | 2 |
| 26750 | RPS6KC1 | 3 |
| 9020 | MAP3K14 | 3 |
| 5580 | PRKCD | 3 |
| 4140 | MARK3 | 3 |
| 9759 | HDAC4 | 3 |
| 1452 | CSNK1A1 | 2 |
| 8714 | ABCC3 | 2 |
| 57510 | XPO5 | 1 |
| 1973 | EIF4A1 | 2 |
| 8859 | STK19 | 1 |
| 79705 | LRRK1 | 3 |
| 6464 | SHC1 | 2 |
| 6037 | RNASE3 | 2 |
| 9472 | AKAP6 | 2 |
| 130497 | OSR1 | 6 |
| 9590 | AKAP12 | 1 |
| 3685 | ITGAV | 3 |
| 6917 | TCEA1 | 1 |
| 80243 | PREX2 | 3 |
| 472 | ATM | 2 |
| 28996 | HIPK2 | 3 |
| 2521 | FUS | 1 |
| 84433 | CARD11 | 3 |
| 9096 | TBX18 | 3 |
| 8038 | ADAM12 | 2 |
| 54986 | ULK4 | 6 |
| 1123 | CHN1 | 1 |
| 1496 | CTNNA2 | 2 |
| 7010 | TEK | 6 |
| 898 | CCNE1 | 4 |
| 2066 | ERBB4 | 3 |
| 5327 | PLAT | 2 |
| 10413 | YAP1 | 1 |
| 1029 | CDKN2A | 1 |
| 9794 | MAML1 | 1 |
| 27436 | EML4 | 2 |
| 8576 | STK16 | 1 |
| 5336 | PLCG2 | 6 |
| 11143 | KAT7 | 2 |
| 27347 | STK39 | 3 |
| 7157 | TP53 | 1 |
| 7704 | ZBTB16 | 1 |
| 4088 | SMAD3 | 1 |
| 4173 | MCM4 | 1 |
| 2322 | FLT3 | 1 |
| 4857 | NOVA1 | 1 |
| 57410 | SCYL1 | 1 |
| 5910 | RAP1GDS1 | 6 |
| 3791 | KDR | 1 |
| 10114 | HIPK3 | 3 |
| 836 | CASP3 | 1 |
| 1019 | CDK4 | 3 |
| 11213 | IRAK3 | 3 |
| 9967 | THRAP3 | 2 |
| 8833 | GMPS | 3 |
| 8874 | ARHGEF7 | 3 |
| 2309 | FOXO3 | 3 |
| 369 | ARAF | 1 |
| 3572 | IL6ST | 1 |
| 57188 | ADAMTSL3 | 1 |
| 55589 | BMP2K | 2 |
| 57591 | MRTFA | 2 |
| 136332 | LRGUK | 5 |
| 4436 | MSH2 | 5 |
| 1656 | DDX6 | 2 |
| 984 | CDK11B | 5 |
| 23365 | ARHGEF12 | 3 |
| 2081 | ERN1 | 4 |
| 84181 | CHD6 | 3 |
| 57578 | UNC79 | 4 |
| 3643 | INSR | 3 |
| 57111 | RAB25 | 1 |
| 2175 | FANCA | 3 |
| 5371 | PML | 3 |
| 170692 | ADAMTS18 | 1 |
| 4139 | MARK1 | 3 |
| 23373 | CRTC1 | 2 |
| 285220 | EPHA6 | 4 |
| 51366 | UBR5 | 3 |
| 3426 | CFI | 2 |
| 2047 | EPHB1 | 1 |
| 501 | ALDH7A1 | 3 |
| 7786 | MAP3K12 | 1 |
| 10926 | DBF4 | 2 |
| 10769 | PLK2 | 2 |
| 57144 | PAK5 | 1 |
| 5578 | PRKCA | 3 |
| 4214 | MAP3K1 | 1 |
| 3702 | ITK | 1 |
| 1198 | CLK3 | 3 |
| 3239 | HOXD13 | 3 |
| 6046 | BRD2 | 3 |
| 1514 | CTSL | 1 |
| 5034 | P4HB | 2 |
| 1000 | CDH2 | 1 |
| 8202 | NCOA3 | 1 |
| 2318 | FLNC | 2 |
| 10565 | ARFGEF1 | 1 |
| 5530 | PPP3CA | 6 |
| 26166 | RGS22 | 2 |
| 54894 | RNF43 | 1 |
| 7075 | TIE1 | 3 |
| 1017 | CDK2 | 1 |
| 744 | MPPED2 | 3 |
| 1956 | EGFR | 2 |
| 157680 | VPS13B | 2 |
| 841 | CASP8 | 3 |
| 3308 | HSPA4 | 3 |
| 10461 | MERTK | 3 |
| 4684 | NCAM1 | 2 |
| 26278 | SACS | 2 |
| 896 | CCND3 | 3 |
| 29951 | PDZRN4 | 1 |
| 6446 | SGK1 | 3 |
| 204851 | HIPK1 | 3 |
| 3635 | INPP5D | 1 |
| 1653 | DDX1 | 1 |
| 8900 | CCNA1 | 1 |
| 5187 | PER1 | 4 |
| 375056 | MIA3 | 3 |
| 27330 | RPS6KA6 | 1 |
| 7189 | TRAF6 | 3 |
| 23005 | MAPKBP1 | 3 |
| 673 | BRAF | 1 |
| 4790 | NFKB1 | 3 |
| 988 | CDC5L | 2 |
| 23532 | PRAME | 3 |
| 4863 | NPAT | 2 |
| 57538 | ALPK3 | 2 |
| 3485 | IGFBP2 | 1 |
| 120892 | LRRK2 | 2 |
| 89795 | NAV3 | 2 |
| 7027 | TFDP1 | 1 |
| 867 | CBL | 2 |
| 6095 | RORA | 1 |
| 7468 | NSD2 | 2 |
| 8029 | CUBN | 3 |
| 11184 | MAP4K1 | 1 |
| 5378 | PMS1 | 3 |
| 157 | GRK3 | 1 |
| 23598 | PATZ1 | 3 |
| 23049 | SMG1 | 1 |
| 10010 | TANK | 2 |
| 8312 | AXIN1 | 3 |
| 10752 | CHL1 | 3 |
| 23476 | BRD4 | 3 |
| 5728 | PTEN | 3 |
| 57521 | RPTOR | 3 |
| 7155 | TOP2B | 1 |
| 80124 | VCPIP1 | 6 |
| 667 | DST | 2 |
| 115701 | ALPK2 | 6 |
| 83666 | PARP9 | 3 |
| 140803 | TRPM6 | 4 |
| 4317 | MMP8 | 2 |
| 2648 | KAT2A | 1 |
| 890 | CCNA2 | 2 |
| 1950 | EGF | 4 |
| 2264 | FGFR4 | 3 |
| 658 | BMPR1B | 1 |
| 8522 | GAS7 | 2 |
| 7454 | WAS | 1 |
| 10257 | ABCC4 | 2 |
| 53904 | MYO3A | 5 |
| 29941 | PKN3 | 3 |
| 79012 | CAMKV | 2 |
| 8821 | INPP4B | 2 |
| 51151 | SLC45A2 | 2 |
| 5291 | PIK3CB | 2 |
| 10076 | PTPRU | 1 |
| 126792 | B3GALT6 | 2 |
| 9748 | SLK | 2 |
| 4619 | MYH1 | 3 |
| 332 | BIRC5 | 1 |
| 5581 | PRKCE | 3 |
| 2067 | ERCC1 | 1 |
| 5562 | PRKAA1 | 1 |
| 2041 | EPHA1 | 3 |
| 9021 | SOCS3 | 2 |
| 10111 | RAD50 | 3 |
| 171389 | NLRP6 | 3 |
| 1789 | DNMT3B | 2 |
| 1281 | COL3A1 | 3 |
| 63976 | PRDM16 | 2 |
| 5335 | PLCG1 | 8 |
| 2194 | FASN | 1 |
| 5587 | PRKD1 | 5 |
| 5170 | PDPK1 | 4 |
| 2321 | FLT1 | 1 |
| 22982 | DIP2C | 3 |
| 3709 | ITPR2 | 6 |
| 8899 | PRPF4B | 2 |
| 84254 | CAMKK1 | 5 |
| 8428 | STK24 | 5 |
| 6300 | MAPK12 | 3 |
| 80216 | ALPK1 | 1 |
| 8569 | MKNK1 | 3 |
| 4330 | MN1 | 1 |
| 7913 | DEK | 1 |
| 51167 | CYB5R4 | 2 |
| 1760 | DMPK | 3 |
| 3815 | KIT | 1 |
| 9212 | AURKB | 3 |
| 5054 | SERPINE1 | 1 |
| 2903 | GRIN2A | 1 |
| 4893 | NRAS | 1 |
| 2065 | ERBB3 | 1 |
| 2074 | ERCC6 | 1 |
| 862 | RUNX1T1 | 3 |
| 8661 | EIF3A | 1 |
| 7403 | KDM6A | 1 |
| 1857 | DVL3 | 1 |
| 2258 | FGF13 | 1 |
| 112268437 | LOC112268437 | 2 |
| 255239 | ANKK1 | 3 |
| 7040 | TGFB1 | 1 |
| 30849 | PIK3R4 | 1 |
| 55959 | SULF2 | 3 |
| 2011 | MARK2 | 3 |
| 23072 | HECW1 | 3 |
| 79577 | CDC73 | 2 |
| 8711 | TNK1 | 3 |
| 4040 | LRP6 | 1 |
| 84446 | BRSK1 | 3 |
| 581 | BAX | 1 |
| 8321 | FZD1 | 3 |
| 156 | GRK2 | 2 |
| 4763 | NF1 | 4 |
| 1612 | DAPK1 | 2 |
| 1994 | ELAVL1 | 3 |
| 63893 | UBE2O | 2 |
| 10891 | PPARGC1A | 1 |
| 5288 | PIK3C2G | 4 |
| 2044 | EPHA5 | 4 |
| 5287 | PIK3C2B | 3 |
| 4593 | MUSK | 3 |
| 4629 | MYH11 | 3 |
| 81788 | NUAK2 | 3 |
| 1608 | DGKG | 2 |
| 6868 | ADAM17 | 2 |
| 23112 | TNRC6B | 3 |
| 2444 | FRK | 1 |
| 6426 | SRSF1 | 1 |
| 64328 | XPO4 | 3 |
| 4916 | NTRK3 | 5 |
| 5624 | PROC | 1 |
| 1488 | CTBP2 | 3 |
| 5590 | PRKCZ | 2 |
Gene in drug-gene network: Network Plot
Models in BX-795
CLASSFICATION
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