MYO18B


Summary: The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
myosin XVIIIBMIM:607295Ensembl:ENSG00000133454HGNC:HGNC:18150PA3830022q12.1

GO terms in MYO18B


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0007018microtubule-based movement
CCIEAGO:0005634nucleus
CCIDAGO:0016461unconventional myosin complex
CCIEAGO:0030017sarcomere
MFIEAGO:0003777microtubule motor activity
MFIEAGO:0003779actin binding
MFIEAGO:0005524ATP binding
MFIEAGO:0008017microtubule binding

Gene expression in normal tissue: MYO18B

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MYO18B


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD577BIX012942
iGMDRD506Fedratinib5
iGMDRD562Navitoclax3
iGMDRD871BRD63683
iGMDRD524ISX-91
iGMDRD886Compound 1541A3
iGMDRD60Quinoclamine2
iGMDRD64Parbendazole2
iGMDRD255SB2250023
iGMDRD260FQI-25
iGMDRD137Indisulam3
iGMDRD187BRD98763
iGMDRD219Bax channel blocker2
iGMDRD193Fqi12
iGMDRD61Kinetin riboside6
iGMDRD152179324-69-73
iGMDRD634SCHEMBL26080412
iGMDRD435BI-25364
iGMDRD883CIL55A2
iGMDRD123Isoevodiamine2
iGMDRD280CYTOCHALASIN B6
iGMDRD394BX-7953
iGMDRD420Leucascandrolide A2
iGMDRD126Tipifarnib2
iGMDRD151CHM-14
iGMDRD486Tosedostat1
iGMDRD781Sirolimus3
iGMDRD79Gemcitabine2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MYO18B

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