MYO18B

Summary: The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namemyosin XVIIIB
OMIM IDMIM:607295
Ensembl IDEnsembl:ENSG00000133454
HGNC IDHGNC:HGNC:18150
PHARMGKB IDPA38300
Map Location22q12.1

GO terms in MYO18B


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0007018 microtubule-based movement
CC IEA GO:0005634 nucleus
CC IDA GO:0016461 unconventional myosin complex
CC IEA GO:0030017 sarcomere
MF IEA GO:0003777 microtubule motor activity
MF IEA GO:0003779 actin binding
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Gene expression in normal tissue: MYO18B

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MYO18B


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD577 BIX01294 2
iGMDRD506 Fedratinib 5
iGMDRD562 Navitoclax 3
iGMDRD871 BRD6368 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MYO18B

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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