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iGMDRD280

Canonical SMILES: CC1CCCC(C=CC(=O)OC23C(C=CC1)C(C(=C)C(C2C(NC3=O)CC4=CC=CC=C4)C)O)O

InChI: InChI=1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,31,33H,3,7,9-10,13,17H2,1-2H3,(H,30,34)/b14-8+,16-15+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1

InChI Key: GBOGMAARMMDZGR-TYHYBEHESA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
CYTOCHALASIN B	CHEMBL411729	5311280	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
331	XIAP	5
3696	ITGB8	1
64901	RANBP17	6
8999	CDKL2	3
7074	TIAM1	3
8019	BRD3	2
10460	TACC3	1
81037	CLPTM1L	5
5027	P2RX7	2
79848	CSPP1	3
10221	TRIB1	3
10641	NPRL2	6
23085	ERC1	2
7128	TNFAIP3	1
9261	MAPKAPK2	3
132	ADK	6
6774	STAT3	4
6319	SCD	6
26191	PTPN22	1
7161	TP73	2
7750	ZMYM2	5
4926	NUMA1	2
11183	MAP4K5	4
114801	TMEM200A	3
4627	MYH9	5
10806	SDCCAG8	1
4168	MCF2	8
23513	SCRIB	2
2956	MSH6	3
2200	FBN1	1
4303	FOXO4	3
150465	TTL	3
399	RHOH	3
10783	NEK6	3
1588	CYP19A1	2
1969	EPHA2	1
9149	DYRK1B	2
347365	ITIH6	5
1138	CHRNA5	2
3757	KCNH2	5
51347	TAOK3	3
4750	NEK1	5
5295	PIK3R1	3
23097	CDK19	3
8289	ARID1A	1
80070	ADAMTS20	10
137994	LETM2	6
701	BUB1B	3
26511	CHIC2	2
3939	LDHA	2
11193	WBP4	2
5934	RBL2	3
2335	FN1	3
84700	MYO18B	6
4928	NUP98	1
65061	CDK15	3
53616	ADAM22	2
4312	MMP1	1
9760	TOX	3
3431	SP110	3
4352	MPL	6
9475	ROCK2	5
83942	TSSK1B	3
6597	SMARCA4	5
3551	IKBKB	4
4036	LRP2	7
8780	RIOK3	5
7764	ZNF217	2
10395	DLC1	3
5133	PDCD1	4
11116	FGFR1OP	6
10320	IKZF1	6
9530	BAG4	1
7444	VRK2	2
29888	STRN4	3
6657	SOX2	7
390502	SERPINA2	3
5754	PTK7	4
56776	FMN2	9
5079	PAX5	6
64783	RBM15	2
51684	SUFU	3
4771	NF2	1
4313	MMP2	9
6598	SMARCB1	3
9891	NUAK1	3
4170	MCL1	1
1607	DGKB	3
23213	SULF1	5
3320	HSP90AA1	1
3066	HDAC2	4
23310	NCAPD3	3
6732	SRPK1	4
8749	ADAM18	1
2241	FER	1
341676	NEK5	3
22821	RASA3	9
6318	SERPINB4	2
4092	SMAD7	5
6455	SH3GL1	1
7048	TGFBR2	6
54822	TRPM7	3
577	ADGRB3	2
114783	LMTK3	2
202374	STK32A	2
1813	DRD2	6
11329	STK38	5
5756	TWF1	2
26039	SS18L1	4
2043	EPHA4	3
3727	JUND	3
127933	UHMK1	1
8844	KSR1	6
55023	PHIP	3
1859	DYRK1A	1
23225	NUP210	1
2313	FLI1	2
56164	STK31	2
10013	HDAC6	1
31	ACACA	3
5890	RAD51B	4
10178	TENM1	1
51755	CDK12	1
5596	MAPK4	1
5533	PPP3CC	3
9411	ARHGAP29	2
29998	BICRA	2
1111	CHEK1	2
26576	SRPK3	5
10438	C1D	2
23617	TSSK2	5
6722	SRF	6
5396	PRRX1	2
7373	COL14A1	1
55300	PI4K2B	3
7173	TPO	6
5314	PKHD1	1
51512	GTSE1	6
139378	ADGRG4	2
7158	TP53BP1	6
89910	UBE3B	3
55294	FBXW7	6
974	CD79B	3
2033	EP300	1
54567	DLL4	4
4001	LMNB1	5
8030	CCDC6	3
5664	PSEN2	3
4361	MRE11	1
10746	MAP3K2	1
5914	RARA	3
64324	NSD1	2
83439	TCF7L1	3
1021	CDK6	4
1454	CSNK1E	3
55728	N4BP2	2
3227	HOXC11	3
10006	ABI1	6
57670	KIAA1549	2
284521	OR2L13	6
340156	MYLK4	2
4610	MYCL	14
2115	ETV1	2
5743	PTGS2	9
342667	STAC2	1
342977	NANOS3	3
7025	NR2F1	8
8767	RIPK2	3
169436	STKLD1	1
222484	LNX2	6
8549	LGR5	6
6256	RXRA	3
3714	JAG2	3
32	ACACB	4
8852	AKAP4	3
3556	IL1RAP	4
329	BIRC2	6
8396	PIP4K2B	3
2688	GH1	3
26353	HSPB8	2
22806	IKZF3	13
2242	FES	2
3645	INSRR	6
5468	PPARG	5
200576	PIKFYVE	2
8313	AXIN2	1
6733	SRPK2	3
6091	ROBO1	5
2042	EPHA3	8
1050	CEBPA	4
116986	AGAP2	2
51343	FZR1	2
23255	MTCL1	5
730249	ACOD1	3
10188	TNK2	1
2736	GLI2	3
6198	RPS6KB1	1
695	BTK	2
51804	SIX4	5
4739	NEDD9	3
3688	ITGB1	2
6928	HNF1B	3
284217	LAMA1	6
7424	VEGFC	3
83931	STK40	10
55681	SCYL2	2
4982	TNFRSF11B	6
2045	EPHA7	2
1992	SERPINB1	2
238	ALK	2
7078	TIMP3	3
7428	VHL	2
2064	ERBB2	8
6850	SYK	3
57476	GRAMD1B	3
8395	PIP5K1B	10
26750	RPS6KC1	5
834	CASP1	4
79971	WLS	1
5534	PPP3R1	3
286826	LIN9	9
23191	CYFIP1	3
23387	SIK3	3
4294	MAP3K10	1
783	CACNB2	5
4140	MARK3	4
6416	MAP2K4	3
1452	CSNK1A1	3
8714	ABCC3	3
10400	PEMT	2
5286	PIK3C2A	3
6709	SPTAN1	3
158056	MAMDC4	2
2068	ERCC2	3
79705	LRRK1	3
6464	SHC1	2
7166	TPH1	3
9472	AKAP6	5
9590	AKAP12	2
3685	ITGAV	7
80243	PREX2	2
472	ATM	2
83903	HASPIN	4
8148	TAF15	2
28996	HIPK2	8
203054	ADCK5	3
5924	RASGRF2	5
4087	SMAD2	6
8038	ADAM12	2
6792	CDKL5	4
1496	CTNNA2	1
7533	YWHAH	3
5289	PIK3C3	6
898	CCNE1	1
23152	CIC	3
2272	FHIT	7
7867	MAPKAPK3	1
7681	MKRN3	3
839	CASP6	3
51517	NCKIPSD	3
10290	SPEG	2
1029	CDKN2A	1
7184	HSP90B1	1
5108	PCM1	3
11143	KAT7	6
28514	DLL1	3
58508	KMT2C	8
7157	TP53	1
2099	ESR1	5
4088	SMAD3	3
27086	FOXP1	4
4173	MCM4	5
4296	MAP3K11	1
57194	ATP10A	1
25836	NIPBL	1
397	ARHGDIB	3
57410	SCYL1	3
5910	RAP1GDS1	6
3791	KDR	5
10114	HIPK3	3
836	CASP3	3
2329	FMO4	2
93210	PGAP3	2
114788	CSMD3	6
2263	FGFR2	1
2133	EXT3	3
5585	PKN1	1
7249	TSC2	6
7409	VAV1	2
65243	ZFP69B	2
11213	IRAK3	3
84075	FSCB	5
124540	MSI2	3
1045	CDX2	1
105	ADARB2	2
5604	MAP2K1	3
4869	NPM1	2
1102	RCBTB2	1
9088	PKMYT1	3
23043	TNIK	2
5164	PDK2	3
2309	FOXO3	5
7038	TG	2
369	ARAF	2
4921	DDR2	3
2177	FANCD2	1
6197	RPS6KA3	5
57188	ADAMTSL3	7
57105	CYSLTR2	2
55589	BMP2K	3
65125	WNK1	2
57591	MRTFA	2
4436	MSH2	7
50945	TBX22	6
676	BRDT	3
1656	DDX6	6
984	CDK11B	5
5650	KLK7	6
7175	TPR	2
5871	MAP4K2	2
9401	RECQL4	3
54106	TLR9	3
80205	CHD9	3
3718	JAK3	3
2081	ERN1	3
57578	UNC79	6
4026	LPP	6
8997	KALRN	6
4437	MSH3	5
23269	MGA	4
57551	TAOK1	8
2175	FANCA	2
5371	PML	9
4089	SMAD4	2
51284	TLR7	3
170692	ADAMTS18	6
7471	WNT1	2
6654	SOS1	7
672	BRCA1	2
2060	EPS15	3
2668	GDNF	6
2737	GLI3	3
4139	MARK1	2
78989	COLEC11	2
23373	CRTC1	2
285220	EPHA6	2
546	ATRX	1
51366	UBR5	3
3417	IDH1	4
2047	EPHB1	2
5069	PAPPA	3
7786	MAP3K12	2
10926	DBF4	4
10769	PLK2	3
64840	PORCN	2
4958	OMD	4
5578	PRKCA	5
8216	LZTR1	6
440275	EIF2AK4	2
1198	CLK3	5
9972	NUP153	3
5290	PIK3CA	7
92335	STRADA	2
1514	CTSL	4
2931	GSK3A	4
5034	P4HB	2
1000	CDH2	9
4145	MATK	3
253260	RICTOR	5
5366	PMAIP1	3
2318	FLNC	3
64919	BCL11B	4
5530	PPP3CA	2
675	BRCA2	1
7075	TIE1	2
8445	DYRK2	4
157680	VPS13B	1
841	CASP8	4
64750	SMURF2	2
90956	ADCK2	3
2624	GATA2	2
5789	PTPRD	3
842	CASP9	3
1459	CSNK2A2	1
10461	MERTK	1
1031	CDKN2C	2
894	CCND2	1
5462	POU5F1B	4
29951	PDZRN4	5
6776	STAT5A	3
51265	CDKL3	2
51701	NLK	3
3553	IL1B	2
833	CARS	9
1594	CYP27B1	2
5747	PTK2	3
2189	FANCG	3
204851	HIPK1	6
1653	DDX1	2
8900	CCNA1	2
1544	CYP1A2	3
91754	NEK9	2
93627	TBCK	6
7189	TRAF6	4
3949	LDLR	6
23005	MAPKBP1	3
10186	LHFPL6	1
7153	TOP2A	6
1213	CLTC	7
4790	NFKB1	4
6011	GRK1	2
84879	MFSD2A	15
988	CDC5L	1
4863	NPAT	2
780	DDR1	3
83452	RAB33B	8
57538	ALPK3	5
6502	SKP2	3
339345	NANOS2	1
120892	LRRK2	5
100272147	CMC4	10
89795	NAV3	2
65268	WNK2	2
79184	BRCC3	3
6095	RORA	4
146057	TTBK2	3
57507	ZNF608	5
84441	MAML2	6
4968	OGG1	3
7468	NSD2	1
8029	CUBN	8
9113	LATS1	2
5294	PIK3CG	1
1024	CDK8	3
7849	PAX8	3
4298	MLLT1	3
5979	RET	3
9321	TRIP11	2
10253	SPRY2	6
9843	HEPH	1
11262	SP140	2
157	GRK3	2
23742	NPAP1	3
23049	SMG1	3
10010	TANK	2
55521	TRIM36	3
10752	CHL1	5
57521	RPTOR	10
208	AKT2	4
51592	TRIM33	3
7030	TFE3	3
5595	MAPK3	2
8888	MCM3AP	4
7155	TOP2B	3
1869	E2F1	3
80124	VCPIP1	3
4914	NTRK1	3
667	DST	2
23281	MTUS2	5
115701	ALPK2	4
5594	MAPK1	3
3554	IL1R1	1
83666	PARP9	3
140803	TRPM6	5
6146	RPL22	5
2324	FLT4	3
9135	RABEP1	5
1950	EGF	6
2264	FGFR4	2
177	AGER	2
658	BMPR1B	3
3678	ITGA5	1
1676	DFFA	3
2870	GRK6	7
9344	TAOK2	1
8301	PICALM	3
23090	ZNF423	3
6498	SKIL	4
28954	REM1	3
1018	CDK3	3
8522	GAS7	4
79834	PEAK1	1
7465	WEE1	3
2119	ETV5	6
7059	THBS3	1
10257	ABCC4	5
23389	MED13L	2
10562	OLFM4	6
29959	NRBP1	2
53904	MYO3A	2
8648	NCOA1	6
387	RHOA	1
29941	PKN3	1
79012	CAMKV	2
3161	HMMR	2
54861	SNRK	1
128869	PIGU	7
8821	INPP4B	5
10243	GPHN	3
8394	PIP5K1A	3
3627	CXCL10	3
2353	FOS	3
286151	FBXO43	3
1662	DDX10	4
5588	PRKCQ	4
4297	KMT2A	2
3611	ILK	3
10076	PTPRU	2
558	AXL	2
7248	TSC1	5
126792	B3GALT6	6
9748	SLK	3
4619	MYH1	1
83417	FCRL4	4
57680	CHD8	5
2869	GRK5	3
2041	EPHA1	3
2317	FLNB	1
9021	SOCS3	3
10111	RAD50	3
9223	MAGI1	3
5395	PMS2	1
860	RUNX2	3
778	CACNA1F	2
171389	NLRP6	3
53353	LRP1B	9
7094	TLN1	1
3181	HNRNPA2B1	3
9659	PDE4DIP	4
9201	DCLK1	5
63976	PRDM16	3
283455	KSR2	2
6093	ROCK1	8
5335	PLCG1	2
2130	EWSR1	4
2776	GNAQ	3
4628	MYH10	1
5927	KDM5A	5
4215	MAP3K3	3
1719	DHFR	5
5583	PRKCH	2
5589	PRKCSH	4
5170	PDPK1	3
1975	EIF4B	3
6196	RPS6KA2	5
57448	BIRC6	1
2131	EXT1	3
8317	CDC7	2
3717	JAK2	5
22982	DIP2C	3
7099	TLR4	1
2157	F8	5
53335	BCL11A	3
5506	PPP1R3A	6
79837	PIP4K2C	3
3709	ITPR2	5
57147	SCYL3	2
6778	STAT6	5
4067	LYN	2
6194	RPS6	3
65267	WNK3	4
84254	CAMKK1	3
8428	STK24	5
3552	IL1A	2
80216	ALPK1	2
5932	RBBP8	5
3977	LIFR	5
5915	RARB	4
7112	TMPO	3
4261	CIITA	5
3656	IRAK2	1
4330	MN1	3
84072	HORMAD1	4
170685	NUDT10	3
80781	COL18A1	2
8536	CAMK1	1
2122	MECOM	5
51167	CYB5R4	8
1760	DMPK	2
5087	PBX1	8
3815	KIT	3
5054	SERPINE1	1
2903	GRIN2A	4
5925	RB1	1
4666	NACA	3
1515	CTSV	2
4893	NRAS	5
1209	CLPTM1	1
2065	ERBB3	6
3131	HLF	2
25	ABL1	3
862	RUNX1T1	3
3691	ITGB4	1
1576	CYP3A4	3
7403	KDM6A	2
54790	TET2	1
1234	CCR5	2
2308	FOXO1	2
4439	MSH5	1
2534	FYN	1
81629	TSSK3	1
7508	XPC	8
112268437	LOC112268437	2
8841	HDAC3	2
197259	MLKL	1
255239	ANKK1	2
7040	TGFB1	3
55959	SULF2	4
4915	NTRK2	6
9262	STK17B	3
139604	MAGEB16	2
3237	HOXD11	3
2073	ERCC5	2
79577	CDC73	3
8711	TNK1	3
84446	BRSK1	5
1013	CDH15	3
3092	HIP1	4
55746	NUP133	3
8321	FZD1	2
156	GRK2	6
57697	FANCM	7
1612	DAPK1	2
5260	PHKG1	10
1994	ELAVL1	3
1840	DTX1	3
6886	TAL1	3
10891	PPARGC1A	3
440270	GOLGA8B	3
5288	PIK3C2G	5
57096	RPGRIP1	3
2044	EPHA5	6
5287	PIK3C2B	2
4593	MUSK	8
4629	MYH11	3
81788	NUAK2	5
3265	HRAS	8
6868	ADAM17	9
27255	CNTN6	3
1499	CTNNB1	8
2444	FRK	10
27151	CPAMD8	2
64328	XPO4	3
2892	GRIA3	12
2886	GRB7	4
167359	NIM1K	3
11035	RIPK3	3
4486	MST1R	3
2904	GRIN2B	3

Gene in drug-gene network: Network Plot

Models in CYTOCHALASIN B

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.