CSNK1E
Summary: The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:600863 Ensembl IDEnsembl:ENSG00000213923 HGNC IDHGNC:HGNC:2453 PHARMGKB IDPA26953 Map Location22q13.1 | |||||
GO terms in CSNK1E
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | IDA | GO:0004672 | protein kinase activity |
| MF | ISS | GO:0004672 | protein kinase activity |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IDA | GO:0004674 | protein serine/threonine kinase activity |
| MF | TAS | GO:0004674 | protein serine/threonine kinase activity |
Gene expression in normal tissue: CSNK1E
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CSNK1E
Database | Pathway ID | Pathway Des. |
|---|---|---|
| netpath | Pathway_Wnt | Wnt |
| pid | betacatenin_deg_pathway | Degradation of beta catenin |
| pid | circadianpathway | Circadian rhythm pathway |
| pid | foxopathway | FoxO family signaling |
| pid | hedgehog_glipathway | Hedgehog signaling events mediated by Gli proteins |
| pid | p53regulationpathway | p53 pathway |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CSNK1E
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
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