GO terms in TRIB1


Term TypeEvidence TypeGO Term IDGO Des.
MFTASGO:0004672protein kinase activity
MFIMPGO:0004860protein kinase inhibitor activity
MFIPIGO:0005515protein binding
MFTASGO:0005524ATP binding
MFIPIGO:0008134transcription factor binding
MFIBAGO:0031434mitogen-activated protein kinase kinase binding
MFIDAGO:0031434mitogen-activated protein kinase kinase binding
MFISSGO:0031625ubiquitin protein ligase binding
MFISSGO:0055106ubiquitin-protein transferase regulator activity
CCIBAGO:0005634nucleus
CCIDAGO:0005634nucleus
CCIDAGO:0005737cytoplasm
BPTASGO:0006468protein phosphorylation
BPIMPGO:0006469negative regulation of protein kinase activity
BPIMPGO:0007254JNK cascade
BPIMPGO:0014912negative regulation of smooth muscle cell migration
BPIMPGO:0031665negative regulation of lipopolysaccharide-mediated signaling pathway
BPIBAGO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process
BPISSGO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process
BPIMPGO:0032496response to lipopolysaccharide
BPISSGO:0032496response to lipopolysaccharide
BPIBAGO:0043405regulation of MAP kinase activity
BPIDAGO:0043405regulation of MAP kinase activity
BPIMPGO:0043433negative regulation of DNA-binding transcription factor activity
BPISSGO:0043433negative regulation of DNA-binding transcription factor activity
BPIEAGO:0045645positive regulation of eosinophil differentiation
BPIEAGO:0045651positive regulation of macrophage differentiation
BPIEAGO:0045659negative regulation of neutrophil differentiation
BPIMPGO:0048662negative regulation of smooth muscle cell proliferation

Gene expression in normal tissue: TRIB1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TRIB1


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD193Fqi13
iGMDRD280CYTOCHALASIN B3
iGMDRD466Chaetocin1
iGMDRD126Tipifarnib3
iGMDRD889Compound 7d-cis3
iGMDRD387CHIR-990213
iGMDRD1008SR-II-138A3
iGMDRD425ERASTIN3
iGMDRD772BRD47703
iGMDRD781Sirolimus3
iGMDRD100Zebularine4
iGMDRD188Piperlongumine3
iGMDRD74Idarubicin3
iGMDRD887Compound 23 citrate3
iGMDRD577BIX012943
iGMDRD780PP-303
iGMDRD398Sepantronium3
iGMDRD690PRIMA-1MET3
iGMDRD356PNU-746543
iGMDRD23Gossypol1
iGMDRD451Serdemetan3
iGMDRD171Pemetrexed3
iGMDRD8012,4-dideoxy-DC-45-A23
iGMDRD294Batimastat3
iGMDRD132(-)-gallocatechin-3-O-gallate1
iGMDRD512nutlin 33
iGMDRD607Ubistatin B3
iGMDRD532Olaparib3
iGMDRD345Compound 10b [PMID: 11504634]1
iGMDRD871BRD63683
iGMDRD329Merck603
iGMDRD137Indisulam3
iGMDRD220fumonisin B13
iGMDRD6AM-5803
iGMDRD213SMR0000686503

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TRIB1

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