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iGMDRD780

Canonical SMILES: CC(C)N1C2=C(C(=N1)C3=CC(=CC=C3)C(=O)NC4=NCCC4)C(=NC=N2)N

InChI: InChI=1S/C19H21N7O/c1-11(2)26-18-15(17(20)22-10-23-18)16(25-26)12-5-3-6-13(9-12)19(27)24-14-7-4-8-21-14/h3,5-6,9-11H,4,7-8H2,1-2H3,(H2,20,22,23)(H,21,24,27)

InChI Key: RWRBSEISHUTNQL-UHFFFAOYSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
PP-30	73707400	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
8999	CDKL2	3
7074	TIAM1	1
5027	P2RX7	3
10221	TRIB1	3
10641	NPRL2	3
23085	ERC1	1
21	ABCA3	2
4926	NUMA1	2
4627	MYH9	4
5546	PRCC	3
8929	PHOX2B	3
1969	EPHA2	3
347365	ITIH6	3
3845	KRAS	10
1138	CHRNA5	3
4750	NEK1	5
26511	CHIC2	2
3939	LDHA	2
25778	DSTYK	3
53616	ADAM22	3
7764	ZNF217	4
2176	FANCC	2
5133	PDCD1	1
390502	SERPINA2	6
5079	PAX5	3
4170	MCL1	1
23213	SULF1	2
22853	LMTK2	3
7253	TSHR	1
7098	TLR3	3
6732	SRPK1	4
5298	PI4KB	4
3841	KPNA5	1
7555	CNBP	3
2043	EPHA4	3
5467	PPARD	4
5788	PTPRC	3
2313	FLI1	2
56164	STK31	2
5596	MAPK4	3
9411	ARHGAP29	4
5074	PAWR	3
11122	PTPRT	1
7373	COL14A1	6
55351	STK32B	2
7173	TPO	2
5314	PKHD1	2
51512	GTSE1	2
974	CD79B	3
10818	FRS2	3
102	ADAM10	1
22861	NLRP1	3
284521	OR2L13	1
5743	PTGS2	1
5607	MAP2K5	3
122011	CSNK1A1L	1
57787	MARK4	2
646643	SBK2	3
1586	CYP17A1	2
8549	LGR5	6
1591	CYP24A1	2
8852	AKAP4	1
5613	PRKX	2
329	BIRC2	3
22806	IKZF3	3
3645	INSRR	1
1437	CSF2	3
51343	FZR1	2
9636	ISG15	3
6198	RPS6KB1	2
83990	BRIP1	2
51804	SIX4	6
23405	DICER1	3
171019	ADAMTS19	2
6850	SYK	2
65217	PCDH15	3
55361	PI4K2A	2
23191	CYFIP1	3
783	CACNB2	2
9759	HDAC4	4
57510	XPO5	2
219970	GLYATL2	3
1973	EIF4A1	3
50488	MINK1	3
2068	ERCC2	3
5591	PRKDC	1
157285	PRAG1	1
80243	PREX2	2
8148	TAF15	3
28996	HIPK2	3
5924	RASGRF2	6
4087	SMAD2	2
11344	TWF2	3
7010	TEK	2
5289	PIK3C3	2
91461	PKDCC	3
23152	CIC	2
2066	ERBB4	2
7681	MKRN3	3
904	CCNT1	3
5863	RGL2	1
7184	HSP90B1	2
5108	PCM1	3
139728	PNCK	3
5129	CDK18	2
5336	PLCG2	3
861	RUNX1	3
10018	BCL2L11	3
58508	KMT2C	5
6794	STK11	4
114788	CSMD3	3
2263	FGFR2	1
7249	TSC2	2
11213	IRAK3	2
85481	PSKH2	6
5604	MAP2K1	3
4869	NPM1	3
9088	PKMYT1	6
23043	TNIK	3
5600	MAPK11	5
7038	TG	3
8660	IRS2	1
57188	ADAMTSL3	3
1656	DDX6	2
984	CDK11B	3
5871	MAP4K2	1
3718	JAK3	3
23365	ARHGEF12	2
84181	CHD6	2
57578	UNC79	1
4437	MSH3	6
2071	ERCC3	6
23269	MGA	2
57551	TAOK1	2
6280	S100A9	3
5610	EIF2AK2	2
23469	PHF3	4
4089	SMAD4	2
6654	SOS1	5
10948	STARD3	1
23373	CRTC1	3
546	ATRX	8
3426	CFI	3
2047	EPHB1	1
54756	IL17RD	2
3558	IL2	3
64840	PORCN	1
30827	CXXC1	3
8216	LZTR1	3
3702	ITK	3
3239	HOXD13	3
3562	IL3	4
1000	CDH2	2
8202	NCOA3	2
4293	MAP3K9	10
5366	PMAIP1	3
5045	FURIN	2
10565	ARFGEF1	7
64919	BCL11B	6
7075	TIE1	2
1956	EGFR	6
4609	MYC	3
90956	ADCK2	6
5789	PTPRD	4
1459	CSNK2A2	3
10461	MERTK	2
4684	NCAM1	3
29951	PDZRN4	1
6776	STAT5A	3
51265	CDKL3	1
2189	FANCG	1
1544	CYP1A2	1
7132	TNFRSF1A	3
3949	LDLR	1
1981	EIF4G1	2
5781	PTPN11	8
23532	PRAME	4
4863	NPAT	2
780	DDR1	2
120892	LRRK2	5
79184	BRCC3	2
6095	RORA	5
57507	ZNF608	3
1677	DFFB	2
93273	LEMD1	2
8626	TP63	1
9113	LATS1	2
5979	RET	3
8491	MAP4K3	2
55290	BRF2	3
266747	RGL4	3
8621	CDK13	2
23049	SMG1	3
10010	TANK	3
23476	BRD4	3
51592	TRIM33	3
7030	TFE3	3
4004	LMO1	3
284086	NEK8	1
3554	IL1R1	2
23542	MAPK8IP2	3
2188	FANCF	2
5896	RAG1	1
23090	ZNF423	3
6498	SKIL	2
7273	TTN	2
8522	GAS7	3
6787	NEK4	1
79012	CAMKV	1
128869	PIGU	1
10243	GPHN	2
22843	PPM1E	2
8394	PIP5K1A	2
65018	PINK1	3
23305	ACSL6	4
51151	SLC45A2	3
5291	PIK3CB	5
126792	B3GALT6	2
83417	FCRL4	4
2690	GHR	1
9021	SOCS3	3
9223	MAGI1	1
860	RUNX2	2
53353	LRP1B	3
3181	HNRNPA2B1	2
9201	DCLK1	2
283455	KSR2	2
6093	ROCK1	3
3557	IL1RN	6
2130	EWSR1	1
2194	FASN	3
598	BCL2L1	1
1719	DHFR	10
5583	PRKCH	2
5589	PRKCSH	2
5170	PDPK1	4
6196	RPS6KA2	2
3717	JAK2	2
22982	DIP2C	3
3709	ITPR2	3
8899	PRPF4B	2
23301	EHBP1	2
3552	IL1A	3
80216	ALPK1	4
3977	LIFR	1
4261	CIITA	3
23512	SUZ12	1
7046	TGFBR1	1
7913	DEK	1
51167	CYB5R4	1
5925	RB1	1
4217	MAP3K5	3
5584	PRKCI	1
54790	TET2	2
2308	FOXO1	1
255239	ANKK1	2
4205	MEF2A	2
7040	TGFB1	2
55959	SULF2	4
2011	MARK2	3
4915	NTRK2	3
142	PARP1	2
2261	FGFR3	2
23072	HECW1	6
5567	PRKACB	3
4841	NONO	3
595	CCND1	2
4763	NF1	2
4591	TRIM37	2
10891	PPARGC1A	5
5288	PIK3C2G	3
5287	PIK3C2B	3
2280	FKBP1A	3
4629	MYH11	6
814	CAMK4	3
30811	HUNK	6
6943	TCF21	3
699	BUB1	3
23112	TNRC6B	1
2178	FANCE	4
27255	CNTN6	1
29110	TBK1	3
2444	FRK	2
27151	CPAMD8	2
56155	TEX14	3
2892	GRIA3	5
5624	PROC	2
5685	PSMA4	3

Gene in drug-gene network: Network Plot

Models in PP-30

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.