PRAG1

Summary: This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NamePEAK1 related, kinase-activating pseudokinase 1
OMIM IDMIM:617344
Ensembl IDEnsembl:ENSG00000275342
HGNC IDHGNC:HGNC:25438
PHARMGKB ID
Map Location8p23.1

GO terms in PRAG1


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0006468 protein phosphorylation
BP ISS GO:0008360 regulation of cell shape
BP ISS GO:0008593 regulation of Notch signaling pathway
BP ISS GO:0010977 negative regulation of neuron projection development
BP IMP GO:0016477 cell migration
BP IEA GO:0018108 peptidyl-tyrosine phosphorylation
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Gene expression in normal tissue: PRAG1

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PRAG1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD698 Neratinib 1
iGMDRD61 Kinetin riboside 2
iGMDRD237 ABT-751 1
iGMDRD679 Bistramide A 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PRAG1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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