SEARCH

HOME / SEARCH / Dexamethasone

iGMDRD48

Canonical SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C

InChI: InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

InChI Key: UREBDLICKHMUKA-CXSFZGCWSA-N

Loading, please wait...

Standard Name	CHEMBL	Pubchem CID	KEGG Drug ID	DRUGBANK ID	Drug Status	Drug targets (TTD)	Drug Type
Standard NameDexamethasone CHEMBLCHEMBL384467 Pubchem CID5743 KEGG Drug IDD02592 DRUGBANK IDDB01234 Drug StatusAlone Drug targets (TTD)DAP000007 Drug TypeSmall Molecule

Drug Class:

Adrenal Cortex Hormones Adrenals Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Alimentary Tract and Metabolism Anti-Acne Preparations Anti-Acne Preparations for Topical Use Anti-Inflammatory Agents Antiemetics Antineoplastic Agents Antineoplastic Agents, Hormonal Autonomic Agents BCRP/ABCG2 Inhibitors Cardiovascular System Central Nervous System Agents Corticosteroids Corticosteroids for Local Oral Treatment Corticosteroids for Systemic Use Corticosteroids for Systemic Use, Plain Corticosteroids, Dermatological Preparations Corticosteroids, Moderately Potent (Group II)Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (moderate)Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Dermatologicals Gastrointestinal Agents Glucocorticoids Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Hyperglycemia-Associated Agents Immunosuppressive Agents Inducers of Drug Clearance Nasal Preparations Ophthalmological and Otological Preparations Ophthalmologicals Otologicals P-glycoprotein/ABCB1 Inducers P-glycoprotein/ABCB1 Inhibitors P-glycoprotein/ABCB1 Substrates Peripheral Nervous System Agents Polycyclic Compounds Pregnadienes Pregnadienetriols Pregnanes Respiratory System Sensory Organs Steroids Steroids, Fluorinated Stomatological Preparations Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins Vasoprotectives

Drug Targets:

NR3C1 (P04150)NR0B1 (P51843)ANXA1 (P04083)NOS2 (P35228)NR1I2 (O75469)

Drug Pathways:

Neuroactive ligand-receptor interaction

Drug Synonyms:

Dexamethasone beloxil (USAN)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Loading, please wait...

Gene ID	Gene Name	Model Num.
7750	ZMYM2	2
2200	FBN1	1
9706	ULK2	3
5295	PIK3R1	1

Showing 1 to 4 of 51 rows rows per page

Gene in drug-gene network: Network Plot

Models in Dexamethasone

Loading, please wait...

	Model	Level	Reference ID	Tissue	Cancer	Drug	Clinical Response	Source
No matching records found

SITE

DATATYPES

CLASSFICATION

Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.